Pan-cancer analysis of SOX2: Prognostic implications and potential as a therapeutic target in immune checkpoint modulation
This study investigates SOX2 genetic, transcriptomic, and epigenetic alterations across over 30 cancer types. Significant downregulation of SOX2 expression was observed in colorectal adenocarcinoma, esophageal carcinoma, rectum adenocarcinoma, stomach adenocarcinoma, and testicular germ cell tumors,...
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Main Authors: | Shoukai Yu, Lingmei Qian, Liling Xu, Jun Ma |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844025005808 |
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