Determination of Voriconazole Plasma Concentration by HPLC Technique and Evaluating Its Association with Clinical Outcome and Adverse Effects in Patients with Invasive Aspergillosis

Determination of Voriconazole Plasma Concentration by HPLC Technique and Evaluating Its Association with Clinical Outcome and Adverse Effects in Patients with Invasive Aspergillosis

Purpose. Invasive aspergillosis is a prevalent fungal disease, especially in Asian countries with a high mortality rate. Voriconazole (VRZ) is the first choice for invasive aspergillosis treatment. Plasma concentration of this drug is unpredictable and varies among individuals. This variability is i...

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Bibliographic Details
Main Authors:	Sahar Yousefian, Farzaneh Dastan, Majid Marjani, Payam Tabarsi, Saghar Barati, Nahid Shahsavari, Farzad Kobarfard
Format:	Article
Language:	English
Published:	Wiley 2021-01-01
Series:	Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:	http://dx.doi.org/10.1155/2021/5497427
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