Delayed second polar body extrusion increases abnormal cleavage risk and impairs embryonic developmental potential: a retrospective time-lapse study

Delayed second polar body extrusion increases abnormal cleavage risk and impairs embryonic developmental potential: a retrospective time-lapse study

Abstract The purpose of this study was to elucidate the effect of second polar body (Pb2) extrusion time on dynamic cleavage parameters and embryonic developmental potential. Data on a total of 398 cycles from patients who underwent intracytoplasmic sperm injection (ICSI) treatment between September...

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Main Authors: Haifang Liu, Shikai Wang, Xianbao Mao, Jie Qin, Yongyi Pan, Zhengda Li, Xiaohui Zhang, Pingpin Wei, Liangshi Chen, Yueyue Huang, Wen Shi, Liling Liu, Lintao Xue
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Embryonic development
Pregnancy outcome
Second Polar body
Time-lapse
Abnormal cleavage
Online Access:https://doi.org/10.1038/s41598-025-07247-4
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