Dehydroepiandrosterone Decline in Aging Males as a Predictor of Erectile Dysfunction and Mood Disorders in Patients With Benign Prostate Hyperplasia Undergoing Dutasteride Treatment

Age-related decline in dehydroepiandrosterone (DHEA) and its sulfate metabolite, dehydroepiandrosterone-sulfate (DHEAS), affects steroid synthesis in men. DHEA(S) acts as a direct neurosteroid and weak androgen and is the unique steroid unaffected by dutasteride’s inhibitory effect on 5α reductases....

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Bibliographic Details
Main Authors: Maja Sofronievska Glavinov, Senol Tahir, Stefan Arsov
Format: Article
Language:English
Published: SAGE Publishing 2025-08-01
Series:American Journal of Men's Health
Online Access:https://doi.org/10.1177/15579883251365091
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