Using an Aqueous Suspension of <i>Duddingtonia flagrans</i> Chlamydospores and a Hexane Extract of <i>Artemisia cina</i> as Sustainable Methods to Reduce the Fecal Egg Count and Larvae of <i>Haemonchus contortus</i> in the Feces of Periparturient Ewes

This study evaluated the effectiveness of <i>Duddingtonia flagrans</i> chlamydospores and an <i>Artemisia cina</i> hexane extract in reducing <i>Haemonchus contortus</i> fecal egg counts and larvae in periparturient ewes. This study involved five groups of four ew...

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Main Authors: Héctor Alejandro de la Crúz-Crúz, Rosa Isabel Higuera-Piedrahita, Alejandro Zamilpa, Yazmín Alcalá-Canto, Ana Yuridia Ocampo-Gutiérrez, Luis David Arango-de la Pava, María Eugenia López-Arellano, Daniel Hernandez-Patlan, Jorge Alfredo Cuéllar-Ordaz, Pedro Mendoza-de Gives
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pathogens
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Online Access:https://www.mdpi.com/2076-0817/14/2/105
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author Héctor Alejandro de la Crúz-Crúz
Rosa Isabel Higuera-Piedrahita
Alejandro Zamilpa
Yazmín Alcalá-Canto
Ana Yuridia Ocampo-Gutiérrez
Luis David Arango-de la Pava
María Eugenia López-Arellano
Daniel Hernandez-Patlan
Jorge Alfredo Cuéllar-Ordaz
Pedro Mendoza-de Gives
author_facet Héctor Alejandro de la Crúz-Crúz
Rosa Isabel Higuera-Piedrahita
Alejandro Zamilpa
Yazmín Alcalá-Canto
Ana Yuridia Ocampo-Gutiérrez
Luis David Arango-de la Pava
María Eugenia López-Arellano
Daniel Hernandez-Patlan
Jorge Alfredo Cuéllar-Ordaz
Pedro Mendoza-de Gives
author_sort Héctor Alejandro de la Crúz-Crúz
collection DOAJ
description This study evaluated the effectiveness of <i>Duddingtonia flagrans</i> chlamydospores and an <i>Artemisia cina</i> hexane extract in reducing <i>Haemonchus contortus</i> fecal egg counts and larvae in periparturient ewes. This study involved five groups of four ewes: a control group, an ivermectin group, an <i>A. cina</i> oral extract group, a <i>D. flagrans</i> group, and a combined treatment group. Treatments began two weeks before delivery, with ivermectin administered 15 days before delivery. Fecal samples were collected every fifteen days to estimate parasite egg counts per gram of feces (EPG) and assess larvae reductions. The results showed very low EPG values for ivermectin and <i>D. flagrans</i> treatments (175 and 150, respectively). The control and combined treatment groups had EPG values rise to 3000 and 4100 by day 15. The EPG values for the <i>A. cina</i> group reached 850 and 533 in later samplings. Throughout the study, the <i>D. flagrans</i> and <i>A. cina</i> groups maintained low EPG values, with the highest recorded values being 50 and 0, respectively. All treatments significantly reduced the larvae in the fecal cultures: <i>D. flagrans</i> (97.4% reduction), ivermectin (91.4%), <i>Artemisia cina</i> (89.9%), and the combined treatment (84.3%).
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spelling doaj-art-97a0512b5fde44d5b42295f7e9d03f082025-08-20T02:44:53ZengMDPI AGPathogens2076-08172025-01-0114210510.3390/pathogens14020105Using an Aqueous Suspension of <i>Duddingtonia flagrans</i> Chlamydospores and a Hexane Extract of <i>Artemisia cina</i> as Sustainable Methods to Reduce the Fecal Egg Count and Larvae of <i>Haemonchus contortus</i> in the Feces of Periparturient EwesHéctor Alejandro de la Crúz-Crúz0Rosa Isabel Higuera-Piedrahita1Alejandro Zamilpa2Yazmín Alcalá-Canto3Ana Yuridia Ocampo-Gutiérrez4Luis David Arango-de la Pava5María Eugenia López-Arellano6Daniel Hernandez-Patlan7Jorge Alfredo Cuéllar-Ordaz8Pedro Mendoza-de Gives9Laboratory of Helminthology, National Centre for Disciplinary Research in Animal Health and Innocuity (CENID-SAI), National Institute for Research in Forestry, Agriculture, and Livestock, INIFAP-SADER, Jiutepec 62550, MexicoLaboratory 3, Multidisciplinary Research Unit, Superior Studies Faculty at Cuautitlán, National Autonomous University of Mexico (FESC-UNAM), Cuautitlán Izcalli 54714, MexicoSouthern Biomedical Research Center, Mexican Social Security Institute (CIBIS-IMSS), Argentina 1, Col. Centro, Xochitepec 62790, MexicoFaculty of Veterinary Medicine and Zootechnics, National Autonomous University of Mexico, Ciudad de México 04510, MexicoLaboratory of Helminthology, National Centre for Disciplinary Research in Animal Health and Innocuity (CENID-SAI), National Institute for Research in Forestry, Agriculture, and Livestock, INIFAP-SADER, Jiutepec 62550, MexicoLaboratory 3, Multidisciplinary Research Unit, Superior Studies Faculty at Cuautitlán, National Autonomous University of Mexico (FESC-UNAM), Cuautitlán Izcalli 54714, MexicoLaboratory of Helminthology, National Centre for Disciplinary Research in Animal Health and Innocuity (CENID-SAI), National Institute for Research in Forestry, Agriculture, and Livestock, INIFAP-SADER, Jiutepec 62550, MexicoLaboratory 5: LEDEFAR, Multidisciplinary Research Unit, Superior Studies Faculty at Cuautitlán, National Autonomous University of Mexico (FESC-UNAM), Cuautitlán Izcalli 54714, MexicoLaboratory 3, Multidisciplinary Research Unit, Superior Studies Faculty at Cuautitlán, National Autonomous University of Mexico (FESC-UNAM), Cuautitlán Izcalli 54714, MexicoLaboratory of Helminthology, National Centre for Disciplinary Research in Animal Health and Innocuity (CENID-SAI), National Institute for Research in Forestry, Agriculture, and Livestock, INIFAP-SADER, Jiutepec 62550, MexicoThis study evaluated the effectiveness of <i>Duddingtonia flagrans</i> chlamydospores and an <i>Artemisia cina</i> hexane extract in reducing <i>Haemonchus contortus</i> fecal egg counts and larvae in periparturient ewes. This study involved five groups of four ewes: a control group, an ivermectin group, an <i>A. cina</i> oral extract group, a <i>D. flagrans</i> group, and a combined treatment group. Treatments began two weeks before delivery, with ivermectin administered 15 days before delivery. Fecal samples were collected every fifteen days to estimate parasite egg counts per gram of feces (EPG) and assess larvae reductions. The results showed very low EPG values for ivermectin and <i>D. flagrans</i> treatments (175 and 150, respectively). The control and combined treatment groups had EPG values rise to 3000 and 4100 by day 15. The EPG values for the <i>A. cina</i> group reached 850 and 533 in later samplings. Throughout the study, the <i>D. flagrans</i> and <i>A. cina</i> groups maintained low EPG values, with the highest recorded values being 50 and 0, respectively. All treatments significantly reduced the larvae in the fecal cultures: <i>D. flagrans</i> (97.4% reduction), ivermectin (91.4%), <i>Artemisia cina</i> (89.9%), and the combined treatment (84.3%).https://www.mdpi.com/2076-0817/14/2/105<i>Duddingtonia flagrans</i><i>Artemisia cina</i><i>Haemonchus contortus</i>EPG reductionlarvae reduction
spellingShingle Héctor Alejandro de la Crúz-Crúz
Rosa Isabel Higuera-Piedrahita
Alejandro Zamilpa
Yazmín Alcalá-Canto
Ana Yuridia Ocampo-Gutiérrez
Luis David Arango-de la Pava
María Eugenia López-Arellano
Daniel Hernandez-Patlan
Jorge Alfredo Cuéllar-Ordaz
Pedro Mendoza-de Gives
Using an Aqueous Suspension of <i>Duddingtonia flagrans</i> Chlamydospores and a Hexane Extract of <i>Artemisia cina</i> as Sustainable Methods to Reduce the Fecal Egg Count and Larvae of <i>Haemonchus contortus</i> in the Feces of Periparturient Ewes
Pathogens
<i>Duddingtonia flagrans</i>
<i>Artemisia cina</i>
<i>Haemonchus contortus</i>
EPG reduction
larvae reduction
title Using an Aqueous Suspension of <i>Duddingtonia flagrans</i> Chlamydospores and a Hexane Extract of <i>Artemisia cina</i> as Sustainable Methods to Reduce the Fecal Egg Count and Larvae of <i>Haemonchus contortus</i> in the Feces of Periparturient Ewes
title_full Using an Aqueous Suspension of <i>Duddingtonia flagrans</i> Chlamydospores and a Hexane Extract of <i>Artemisia cina</i> as Sustainable Methods to Reduce the Fecal Egg Count and Larvae of <i>Haemonchus contortus</i> in the Feces of Periparturient Ewes
title_fullStr Using an Aqueous Suspension of <i>Duddingtonia flagrans</i> Chlamydospores and a Hexane Extract of <i>Artemisia cina</i> as Sustainable Methods to Reduce the Fecal Egg Count and Larvae of <i>Haemonchus contortus</i> in the Feces of Periparturient Ewes
title_full_unstemmed Using an Aqueous Suspension of <i>Duddingtonia flagrans</i> Chlamydospores and a Hexane Extract of <i>Artemisia cina</i> as Sustainable Methods to Reduce the Fecal Egg Count and Larvae of <i>Haemonchus contortus</i> in the Feces of Periparturient Ewes
title_short Using an Aqueous Suspension of <i>Duddingtonia flagrans</i> Chlamydospores and a Hexane Extract of <i>Artemisia cina</i> as Sustainable Methods to Reduce the Fecal Egg Count and Larvae of <i>Haemonchus contortus</i> in the Feces of Periparturient Ewes
title_sort using an aqueous suspension of i duddingtonia flagrans i chlamydospores and a hexane extract of i artemisia cina i as sustainable methods to reduce the fecal egg count and larvae of i haemonchus contortus i in the feces of periparturient ewes
topic <i>Duddingtonia flagrans</i>
<i>Artemisia cina</i>
<i>Haemonchus contortus</i>
EPG reduction
larvae reduction
url https://www.mdpi.com/2076-0817/14/2/105
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