The influence of a defoaming agent-simeticone on the cleaning and disinfection of endoscope: a prospective real-world study

Background: Simeticone has been extensively utilized in endoscopy examinations and therapies; however, consensus regarding its impact on endoscopy cleaning is still lacking. The aim of this study is to assess the impact of simeticone usage during endoscopic examination on the efficacy of endoscope c...

Full description

Saved in:
Bibliographic Details
Main Authors: Juanjuan Huang, Tingsheng Ling, Junlin Zhang, Lianzhen Wei, Lei Chen, Huiwen Cao, lei wang, Yitong Liu, Dongkun Wen, Danrui Ren, Yang Li
Format: Article
Language:English
Published: Georg Thieme Verlag KG
Series:Endoscopy International Open
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/a-2681-2659
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background: Simeticone has been extensively utilized in endoscopy examinations and therapies; however, consensus regarding its impact on endoscopy cleaning is still lacking. The aim of this study is to assess the impact of simeticone usage during endoscopic examination on the efficacy of endoscope cleaning. Methods: This is a prospective real-world study that involves the use of varying concentrations of simeticone in the endoscope biopsy channel and auxiliary water channel. Results: All simeticone residual amounts and ATP values were analyzed every month in one year. The use of 1% and 2% concentrations of simeticone generally resulted in variations in the residual simeticone levels between the two channels. There is no significant alteration in ATP values in any concentration between the two channels. However, there was a significant difference in ATP values between the two channels at the concentration of 1% simeticone. After one year of usage, suspected adherent were observed in the 2% simeticone group, whereas no crystals were detected adhering to the biopsy channel walls in the 1% group or the control group.Sensitivity analysis suggested that the study results did not differ between the gastroscopy and colonoscopy subgroups. Conclusions: Simeticone may remain in the biopsy channel and the water infusion channel, regardless of whether simeticone is used or not. It is recommended to utilize a concentration of 1% or lower of simeticone when administering it through the biopsy or auxiliary water channels of the endoscope.
ISSN:2364-3722
2196-9736