Effects of Methyl Jasmonate on Flavonoid Accumulation and Physiological Metabolism in Finger Millet (<i>Eleusine coracana</i> L.) Sprouts

Finger millet (<i>Eleusine coracana</i> L.) is a nutrient-dense cereal with high flavonoid content, yet the mechanisms regulating its secondary metabolite biosynthesis remain underexplored. Various exogenous stimuli can readily activate the enzymatic pathways and gene expression associat...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhangqin Ye, Jing Zhang, Xin Tian, Zhengfei Yang, Jiangyu Zhu, Yongqi Yin
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Plants
Subjects:
Online Access:https://www.mdpi.com/2223-7747/14/14/2201
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849418921437822976
author Zhangqin Ye
Jing Zhang
Xin Tian
Zhengfei Yang
Jiangyu Zhu
Yongqi Yin
author_facet Zhangqin Ye
Jing Zhang
Xin Tian
Zhengfei Yang
Jiangyu Zhu
Yongqi Yin
author_sort Zhangqin Ye
collection DOAJ
description Finger millet (<i>Eleusine coracana</i> L.) is a nutrient-dense cereal with high flavonoid content, yet the mechanisms regulating its secondary metabolite biosynthesis remain underexplored. Various exogenous stimuli can readily activate the enzymatic pathways and gene expression associated with flavonoid biosynthesis in plants, which are regulated by developmental cues. Research has established that methyl jasmonate (MeJA) application enhances secondary metabolite production in plant systems. This investigation examined MeJA’s influence on flavonoid accumulation and physiological responses in finger millet sprouts to elucidate the molecular mechanisms underlying MeJA-mediated flavonoid accumulation. The findings revealed that MeJA treatment significantly suppressed sprout elongation while enhancing the biosynthesis of total flavonoids and phenolic compounds. MeJA treatment triggered oxidative stress responses, with hydrogen peroxide and superoxide anion concentrations increasing 1.84-fold and 1.70-fold compared to control levels at 4 days post-germination. Furthermore, the antioxidant defense mechanisms in finger millet were upregulated following treatment, resulting in significant enhancement of catalase and peroxidase enzymatic activities and corresponding transcript abundance. MeJA application augmented the activities of key phenylpropanoid pathway enzymes—phenylalanine ammonia-lyase (PAL) and cinnamate 4-hydroxylase (C4H)—and upregulated their respective gene expression. At 4 days post-germination, <i>EcPAL</i> and <i>EcC4H</i> transcript levels were elevated 3.67-fold and 2.61-fold, respectively, compared to untreated controls. MeJA treatment significantly induced the expression of downstream structural genes and transcriptional regulators. This study provides a deeper understanding of the mechanism of flavonoid accumulation in foxtail millet induced by MeJA, and lays a foundation for exogenous conditions to promote flavonoid biosynthesis in plants.
format Article
id doaj-art-978d5052424f415aa5faef49d450a285
institution Kabale University
issn 2223-7747
language English
publishDate 2025-07-01
publisher MDPI AG
record_format Article
series Plants
spelling doaj-art-978d5052424f415aa5faef49d450a2852025-08-20T03:32:18ZengMDPI AGPlants2223-77472025-07-011414220110.3390/plants14142201Effects of Methyl Jasmonate on Flavonoid Accumulation and Physiological Metabolism in Finger Millet (<i>Eleusine coracana</i> L.) SproutsZhangqin Ye0Jing Zhang1Xin Tian2Zhengfei Yang3Jiangyu Zhu4Yongqi Yin5College of Food Science and Engineering, Yangzhou University, Yangzhou 225009, ChinaCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225009, ChinaCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225009, ChinaCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225009, ChinaCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225009, ChinaCollege of Food Science and Engineering, Yangzhou University, Yangzhou 225009, ChinaFinger millet (<i>Eleusine coracana</i> L.) is a nutrient-dense cereal with high flavonoid content, yet the mechanisms regulating its secondary metabolite biosynthesis remain underexplored. Various exogenous stimuli can readily activate the enzymatic pathways and gene expression associated with flavonoid biosynthesis in plants, which are regulated by developmental cues. Research has established that methyl jasmonate (MeJA) application enhances secondary metabolite production in plant systems. This investigation examined MeJA’s influence on flavonoid accumulation and physiological responses in finger millet sprouts to elucidate the molecular mechanisms underlying MeJA-mediated flavonoid accumulation. The findings revealed that MeJA treatment significantly suppressed sprout elongation while enhancing the biosynthesis of total flavonoids and phenolic compounds. MeJA treatment triggered oxidative stress responses, with hydrogen peroxide and superoxide anion concentrations increasing 1.84-fold and 1.70-fold compared to control levels at 4 days post-germination. Furthermore, the antioxidant defense mechanisms in finger millet were upregulated following treatment, resulting in significant enhancement of catalase and peroxidase enzymatic activities and corresponding transcript abundance. MeJA application augmented the activities of key phenylpropanoid pathway enzymes—phenylalanine ammonia-lyase (PAL) and cinnamate 4-hydroxylase (C4H)—and upregulated their respective gene expression. At 4 days post-germination, <i>EcPAL</i> and <i>EcC4H</i> transcript levels were elevated 3.67-fold and 2.61-fold, respectively, compared to untreated controls. MeJA treatment significantly induced the expression of downstream structural genes and transcriptional regulators. This study provides a deeper understanding of the mechanism of flavonoid accumulation in foxtail millet induced by MeJA, and lays a foundation for exogenous conditions to promote flavonoid biosynthesis in plants.https://www.mdpi.com/2223-7747/14/14/2201flavonoidfinger millet sproutsmethyl jasmonate
spellingShingle Zhangqin Ye
Jing Zhang
Xin Tian
Zhengfei Yang
Jiangyu Zhu
Yongqi Yin
Effects of Methyl Jasmonate on Flavonoid Accumulation and Physiological Metabolism in Finger Millet (<i>Eleusine coracana</i> L.) Sprouts
Plants
flavonoid
finger millet sprouts
methyl jasmonate
title Effects of Methyl Jasmonate on Flavonoid Accumulation and Physiological Metabolism in Finger Millet (<i>Eleusine coracana</i> L.) Sprouts
title_full Effects of Methyl Jasmonate on Flavonoid Accumulation and Physiological Metabolism in Finger Millet (<i>Eleusine coracana</i> L.) Sprouts
title_fullStr Effects of Methyl Jasmonate on Flavonoid Accumulation and Physiological Metabolism in Finger Millet (<i>Eleusine coracana</i> L.) Sprouts
title_full_unstemmed Effects of Methyl Jasmonate on Flavonoid Accumulation and Physiological Metabolism in Finger Millet (<i>Eleusine coracana</i> L.) Sprouts
title_short Effects of Methyl Jasmonate on Flavonoid Accumulation and Physiological Metabolism in Finger Millet (<i>Eleusine coracana</i> L.) Sprouts
title_sort effects of methyl jasmonate on flavonoid accumulation and physiological metabolism in finger millet i eleusine coracana i l sprouts
topic flavonoid
finger millet sprouts
methyl jasmonate
url https://www.mdpi.com/2223-7747/14/14/2201
work_keys_str_mv AT zhangqinye effectsofmethyljasmonateonflavonoidaccumulationandphysiologicalmetabolisminfingermilletieleusinecoracanailsprouts
AT jingzhang effectsofmethyljasmonateonflavonoidaccumulationandphysiologicalmetabolisminfingermilletieleusinecoracanailsprouts
AT xintian effectsofmethyljasmonateonflavonoidaccumulationandphysiologicalmetabolisminfingermilletieleusinecoracanailsprouts
AT zhengfeiyang effectsofmethyljasmonateonflavonoidaccumulationandphysiologicalmetabolisminfingermilletieleusinecoracanailsprouts
AT jiangyuzhu effectsofmethyljasmonateonflavonoidaccumulationandphysiologicalmetabolisminfingermilletieleusinecoracanailsprouts
AT yongqiyin effectsofmethyljasmonateonflavonoidaccumulationandphysiologicalmetabolisminfingermilletieleusinecoracanailsprouts