The Difficulties of Differential Diagnosis of the Bronchial Obstruction Syndrome
Bronchial obstructive syndrome is a violation of bronchial patency of functional or organic origin, which is manifested by shortness of breath, suffocation attacks, cough, tachycardia. The most common cause of bronchial obstructive syndrome is chronic obstructive pulmonary disease and bronchial asth...
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SINAPS LLC
2021-08-01
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| Series: | Архивъ внутренней медицины |
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| author | I. V. Demko M. G. Mamaeva A. Yu. Kraposhina E. A. Sobko N. V. Gordeeva S. A. Sidorov V. V. Dyatlovskij |
| author_facet | I. V. Demko M. G. Mamaeva A. Yu. Kraposhina E. A. Sobko N. V. Gordeeva S. A. Sidorov V. V. Dyatlovskij |
| author_sort | I. V. Demko |
| collection | DOAJ |
| description | Bronchial obstructive syndrome is a violation of bronchial patency of functional or organic origin, which is manifested by shortness of breath, suffocation attacks, cough, tachycardia. The most common cause of bronchial obstructive syndrome is chronic obstructive pulmonary disease and bronchial asthma. In some cases, the cause of bronchial obstruction is tumors or tumor metastases to the lungs. The article describes a clinical case of bronchial obstructive syndrome, showing that all patients with bronchial asthma, in the absence of an effect from the prescribed adequate basic therapy, with no control over the disease, should be well examined for an alternative diagnosis. In our case, a thorough examination of the patient allowed the allergist to diagnose central lung cancer with metastases to the lymph nodes of the mediastinum. A feature of the case is the primary resistance to tyrosine kinase inhibitors, revealed during a genetic study, which determined the scheme of further polychemotherapy. This clinical case proves the need for differential diagnosis, with a comprehensive approach and the use of various examination methods. |
| format | Article |
| id | doaj-art-97896c2a0eda4ba28dea130ffdd5611b |
| institution | Kabale University |
| issn | 2226-6704 2411-6564 |
| language | Russian |
| publishDate | 2021-08-01 |
| publisher | SINAPS LLC |
| record_format | Article |
| series | Архивъ внутренней медицины |
| spelling | doaj-art-97896c2a0eda4ba28dea130ffdd5611b2025-08-20T04:00:01ZrusSINAPS LLCАрхивъ внутренней медицины2226-67042411-65642021-08-0111429229610.20514/2226-6704-2021-11-4-292-296854The Difficulties of Differential Diagnosis of the Bronchial Obstruction SyndromeI. V. Demko0M. G. Mamaeva1A. Yu. Kraposhina2E. A. Sobko3N. V. Gordeeva4S. A. Sidorov5V. V. Dyatlovskij6Professor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; Krasnoyarsk Clinical Regional HospitalProfessor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; Krasnoyarsk Clinical Regional HospitalProfessor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; Krasnoyarsk Clinical Regional HospitalProfessor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; Krasnoyarsk Clinical Regional HospitalProfessor V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; Krasnoyarsk Clinical Regional HospitalProfessor V.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityProfessor V.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityBronchial obstructive syndrome is a violation of bronchial patency of functional or organic origin, which is manifested by shortness of breath, suffocation attacks, cough, tachycardia. The most common cause of bronchial obstructive syndrome is chronic obstructive pulmonary disease and bronchial asthma. In some cases, the cause of bronchial obstruction is tumors or tumor metastases to the lungs. The article describes a clinical case of bronchial obstructive syndrome, showing that all patients with bronchial asthma, in the absence of an effect from the prescribed adequate basic therapy, with no control over the disease, should be well examined for an alternative diagnosis. In our case, a thorough examination of the patient allowed the allergist to diagnose central lung cancer with metastases to the lymph nodes of the mediastinum. A feature of the case is the primary resistance to tyrosine kinase inhibitors, revealed during a genetic study, which determined the scheme of further polychemotherapy. This clinical case proves the need for differential diagnosis, with a comprehensive approach and the use of various examination methods.https://www.medarhive.ru/jour/article/view/1273bronchial asthmabronchial obstruction syndrometyrosine kinase inhibitorsnon-small cell lung cancerepidermal growth factor receptor |
| spellingShingle | I. V. Demko M. G. Mamaeva A. Yu. Kraposhina E. A. Sobko N. V. Gordeeva S. A. Sidorov V. V. Dyatlovskij The Difficulties of Differential Diagnosis of the Bronchial Obstruction Syndrome Архивъ внутренней медицины bronchial asthma bronchial obstruction syndrome tyrosine kinase inhibitors non-small cell lung cancer epidermal growth factor receptor |
| title | The Difficulties of Differential Diagnosis of the Bronchial Obstruction Syndrome |
| title_full | The Difficulties of Differential Diagnosis of the Bronchial Obstruction Syndrome |
| title_fullStr | The Difficulties of Differential Diagnosis of the Bronchial Obstruction Syndrome |
| title_full_unstemmed | The Difficulties of Differential Diagnosis of the Bronchial Obstruction Syndrome |
| title_short | The Difficulties of Differential Diagnosis of the Bronchial Obstruction Syndrome |
| title_sort | difficulties of differential diagnosis of the bronchial obstruction syndrome |
| topic | bronchial asthma bronchial obstruction syndrome tyrosine kinase inhibitors non-small cell lung cancer epidermal growth factor receptor |
| url | https://www.medarhive.ru/jour/article/view/1273 |
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