Association between Polypharmacy and Depression, Anxiety and Stress in Elderly: A Cross-Sectional Study
Objective: This study aimed to examine the association between polypharmacy and depression, anxiety and stress in elderly. Methods: This cross-sectional study was conducted with 396 elderly admitted to two different hospitals in a province in eastern Türkiye. Information Form and Depression Anxiety...
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| Language: | English |
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Atatürk University
2025-06-01
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| Series: | Journal of Nursology |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/4373688 |
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| author | Ayşenur Sarıaslan Berna Aktaş |
| author_facet | Ayşenur Sarıaslan Berna Aktaş |
| author_sort | Ayşenur Sarıaslan |
| collection | DOAJ |
| description | Objective: This study aimed to examine the association between polypharmacy and depression, anxiety and stress in elderly. Methods: This cross-sectional study was conducted with 396 elderly admitted to two different hospitals in a province in eastern Türkiye. Information Form and Depression Anxiety Stress Scale-21 were used to collect data. The data were obtained between August and September 2023.Results: Polypharmacy was present in 43.7% of the elderly. In the study, it was determined that income status (OR=0.385; %95 GA=0.163-0.909, P=.029), hypertension (OR=3.899; 95% CI=1.606-9.466, P=.003), coronary artery disease (OR=6.677; 95% CI=2.620-17.020, P=.001), diabetes (OR=3.924; 95% CI=1.543-9.981, P=.004), lung disease (OR=8.893; 95% CI=2.909-27.180, P<.001), hyperlipidemia (OR=20.023; 95% CI=5.737-69.887, P<.001), kidney disease (OR=16.514; 95% CI=5.873-46.431, P<.001), thyroid disease (OR=7.213; 95% CI=2.255-23.079, P<.001), cancer (OR=24.783; 95% CI=6.755-90.933, P<.001) and thinking that they were using too much drug (OR=0.484; 95% CI=0.233-1.005, P=.052) were significant risk factors for polypharmacy. It was observed that the presence of depression, anxiety and stress was not a significant risk factor for polypharmacy in the elderly (P>.05). Conclusion: Further study on association between polypharmacy and depression, anxiety and stress in elderly is necessary. In future studies, it is recommended to use more comprehensive measurement tools, to evaluate which group the medicines used by the elderly belong to and to test causality. |
| format | Article |
| id | doaj-art-978512edf2c942768e7b6a23ec730451 |
| institution | Kabale University |
| issn | 2822-2954 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Atatürk University |
| record_format | Article |
| series | Journal of Nursology |
| spelling | doaj-art-978512edf2c942768e7b6a23ec7304512025-08-20T03:47:20ZengAtatürk UniversityJournal of Nursology2822-29542025-06-0128219720510.17049/jnursology.158692755Association between Polypharmacy and Depression, Anxiety and Stress in Elderly: A Cross-Sectional StudyAyşenur Sarıaslan0https://orcid.org/0000-0001-8005-1067Berna Aktaş1https://orcid.org/0000-0002-8722-8299KAFKAS ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ FAKÜLTESİKAFKAS ÜNİVERSİTESİ, SAĞLIK BİLİMLERİ FAKÜLTESİObjective: This study aimed to examine the association between polypharmacy and depression, anxiety and stress in elderly. Methods: This cross-sectional study was conducted with 396 elderly admitted to two different hospitals in a province in eastern Türkiye. Information Form and Depression Anxiety Stress Scale-21 were used to collect data. The data were obtained between August and September 2023.Results: Polypharmacy was present in 43.7% of the elderly. In the study, it was determined that income status (OR=0.385; %95 GA=0.163-0.909, P=.029), hypertension (OR=3.899; 95% CI=1.606-9.466, P=.003), coronary artery disease (OR=6.677; 95% CI=2.620-17.020, P=.001), diabetes (OR=3.924; 95% CI=1.543-9.981, P=.004), lung disease (OR=8.893; 95% CI=2.909-27.180, P<.001), hyperlipidemia (OR=20.023; 95% CI=5.737-69.887, P<.001), kidney disease (OR=16.514; 95% CI=5.873-46.431, P<.001), thyroid disease (OR=7.213; 95% CI=2.255-23.079, P<.001), cancer (OR=24.783; 95% CI=6.755-90.933, P<.001) and thinking that they were using too much drug (OR=0.484; 95% CI=0.233-1.005, P=.052) were significant risk factors for polypharmacy. It was observed that the presence of depression, anxiety and stress was not a significant risk factor for polypharmacy in the elderly (P>.05). Conclusion: Further study on association between polypharmacy and depression, anxiety and stress in elderly is necessary. In future studies, it is recommended to use more comprehensive measurement tools, to evaluate which group the medicines used by the elderly belong to and to test causality.https://dergipark.org.tr/tr/download/article-file/4373688polifarmasidepresyonanksiyetestresyaşlıpolypharmacydepressionanxietystresselderly |
| spellingShingle | Ayşenur Sarıaslan Berna Aktaş Association between Polypharmacy and Depression, Anxiety and Stress in Elderly: A Cross-Sectional Study Journal of Nursology polifarmasi depresyon anksiyete stres yaşlı polypharmacy depression anxiety stress elderly |
| title | Association between Polypharmacy and Depression, Anxiety and Stress in Elderly: A Cross-Sectional Study |
| title_full | Association between Polypharmacy and Depression, Anxiety and Stress in Elderly: A Cross-Sectional Study |
| title_fullStr | Association between Polypharmacy and Depression, Anxiety and Stress in Elderly: A Cross-Sectional Study |
| title_full_unstemmed | Association between Polypharmacy and Depression, Anxiety and Stress in Elderly: A Cross-Sectional Study |
| title_short | Association between Polypharmacy and Depression, Anxiety and Stress in Elderly: A Cross-Sectional Study |
| title_sort | association between polypharmacy and depression anxiety and stress in elderly a cross sectional study |
| topic | polifarmasi depresyon anksiyete stres yaşlı polypharmacy depression anxiety stress elderly |
| url | https://dergipark.org.tr/tr/download/article-file/4373688 |
| work_keys_str_mv | AT aysenursarıaslan associationbetweenpolypharmacyanddepressionanxietyandstressinelderlyacrosssectionalstudy AT bernaaktas associationbetweenpolypharmacyanddepressionanxietyandstressinelderlyacrosssectionalstudy |