Tenosynovial Giant Cell Tumor Involving Quadriceps Muscle – A Case Report of Two Cases
Introduction: Tenosynovial giant cell tumors (TS-GCTs) are benign soft-tissue tumors that arise from the synovium of joints, bursae, and tendon sheath. They are classified into two major forms – localized and diffuse types with varied clinical presentation and treatment protocol. Case Report: A 38-y...
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| Language: | English |
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Indian Orthopaedic Research Group
2025-04-01
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| Series: | Journal of Orthopaedic Case Reports |
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| Online Access: | https://jocr.co.in/wp/2025/04/01/tenosynovial-giant-cell-tumor-involving-quadriceps-muscle-a-case-report-of-two-cases/ |
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| author | Kishore Ragavendra Rajesh J K Giriraj Harshavardhan Sundar Suriyakumar Mohammed Tavfiq U Thiyagarajan Subalakshmi Balasubramanian |
| author_facet | Kishore Ragavendra Rajesh J K Giriraj Harshavardhan Sundar Suriyakumar Mohammed Tavfiq U Thiyagarajan Subalakshmi Balasubramanian |
| author_sort | Kishore Ragavendra Rajesh |
| collection | DOAJ |
| description | Introduction:
Tenosynovial giant cell tumors (TS-GCTs) are benign soft-tissue tumors that arise from the synovium of joints, bursae, and tendon sheath. They are classified into two major forms – localized and diffuse types with varied clinical presentation and treatment protocol.
Case Report:
A 38-year-old gentleman presented with complaints of left thigh swelling and pain since 18 months. He underwent aspiration and a surgical procedure elsewhere without much improvement. Diagnosis was confirmed on magnetic resonance imaging (MRI). Surgical resection was done and specimen was correlated histopathologically. Another 15-year-old boy presented with complaints of right knee pain and swelling since 5 months. MRI was done which showed knee effusion with synovial thickening for which aspiration was done and started on antibiotics but symptoms persisted. Hence, surgical resection and biopsy was done which was confirmed to be TS-GCT. Both patients regained full knee movements postoperatively and were uneventful.
Conclusion:
The mainstay of treatment of TS-GCT diffuse type is complete open surgical resection with role of adjuvant radiotherapy/chemotherapy being controversial. |
| format | Article |
| id | doaj-art-977bcb41d83a4222bcc1cec3aded6c13 |
| institution | OA Journals |
| issn | 2250-0685 2321-3817 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Indian Orthopaedic Research Group |
| record_format | Article |
| series | Journal of Orthopaedic Case Reports |
| spelling | doaj-art-977bcb41d83a4222bcc1cec3aded6c132025-08-20T02:37:09ZengIndian Orthopaedic Research GroupJournal of Orthopaedic Case Reports2250-06852321-38172025-04-0115419219810.13107/jocr.2025.v15.i04.5496Tenosynovial Giant Cell Tumor Involving Quadriceps Muscle – A Case Report of Two CasesKishore Ragavendra RajeshJ K Giriraj HarshavardhanSundar SuriyakumarMohammed TavfiqU ThiyagarajanSubalakshmi BalasubramanianIntroduction: Tenosynovial giant cell tumors (TS-GCTs) are benign soft-tissue tumors that arise from the synovium of joints, bursae, and tendon sheath. They are classified into two major forms – localized and diffuse types with varied clinical presentation and treatment protocol. Case Report: A 38-year-old gentleman presented with complaints of left thigh swelling and pain since 18 months. He underwent aspiration and a surgical procedure elsewhere without much improvement. Diagnosis was confirmed on magnetic resonance imaging (MRI). Surgical resection was done and specimen was correlated histopathologically. Another 15-year-old boy presented with complaints of right knee pain and swelling since 5 months. MRI was done which showed knee effusion with synovial thickening for which aspiration was done and started on antibiotics but symptoms persisted. Hence, surgical resection and biopsy was done which was confirmed to be TS-GCT. Both patients regained full knee movements postoperatively and were uneventful. Conclusion: The mainstay of treatment of TS-GCT diffuse type is complete open surgical resection with role of adjuvant radiotherapy/chemotherapy being controversial.https://jocr.co.in/wp/2025/04/01/tenosynovial-giant-cell-tumor-involving-quadriceps-muscle-a-case-report-of-two-cases/tenosynovial giant cell tumortenosynovial-giant cell tumor of kneediffuse typeopen biopsymagnetic resonance imagingwide resectionradiotherapychemotherapy |
| spellingShingle | Kishore Ragavendra Rajesh J K Giriraj Harshavardhan Sundar Suriyakumar Mohammed Tavfiq U Thiyagarajan Subalakshmi Balasubramanian Tenosynovial Giant Cell Tumor Involving Quadriceps Muscle – A Case Report of Two Cases Journal of Orthopaedic Case Reports tenosynovial giant cell tumor tenosynovial-giant cell tumor of knee diffuse type open biopsy magnetic resonance imaging wide resection radiotherapy chemotherapy |
| title | Tenosynovial Giant Cell Tumor Involving Quadriceps Muscle – A Case Report of Two Cases |
| title_full | Tenosynovial Giant Cell Tumor Involving Quadriceps Muscle – A Case Report of Two Cases |
| title_fullStr | Tenosynovial Giant Cell Tumor Involving Quadriceps Muscle – A Case Report of Two Cases |
| title_full_unstemmed | Tenosynovial Giant Cell Tumor Involving Quadriceps Muscle – A Case Report of Two Cases |
| title_short | Tenosynovial Giant Cell Tumor Involving Quadriceps Muscle – A Case Report of Two Cases |
| title_sort | tenosynovial giant cell tumor involving quadriceps muscle a case report of two cases |
| topic | tenosynovial giant cell tumor tenosynovial-giant cell tumor of knee diffuse type open biopsy magnetic resonance imaging wide resection radiotherapy chemotherapy |
| url | https://jocr.co.in/wp/2025/04/01/tenosynovial-giant-cell-tumor-involving-quadriceps-muscle-a-case-report-of-two-cases/ |
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