Advances in animal models of cognitive impairment secondary to coronary heart disease

Coronary heart disease and cognitive impairment are both major diseases harmful to human health. A large number of studies have shown that coronary heart disease increases the risk of cognitive impairment in patients with the disease. It is of great clinical significance to explore the mechanism, pr...

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Main Authors: Qing WANG, Feng-Lan LIU, Shi-Han XU, Yan-Fei LIU, Yue LIU, Feng-Qin XU
Format: Article
Language:zho
Published: Editorial Office of New Medicine 2022-08-01
Series:Yixue xinzhi zazhi
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Online Access:https://yxxz.whuznhmedj.com/storage/attach/2208/kbjvB6edFl9GihAjing1HdocbISibmtTIEfcPnUZ.pdf
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author Qing WANG
Feng-Lan LIU
Shi-Han XU
Yan-Fei LIU
Yue LIU
Feng-Qin XU
author_facet Qing WANG
Feng-Lan LIU
Shi-Han XU
Yan-Fei LIU
Yue LIU
Feng-Qin XU
author_sort Qing WANG
collection DOAJ
description Coronary heart disease and cognitive impairment are both major diseases harmful to human health. A large number of studies have shown that coronary heart disease increases the risk of cognitive impairment in patients with the disease. It is of great clinical significance to explore the mechanism, prevention and treatment of such comorbidities. Research on the pathogenesis and treat-ment of cognitive impairment secondary to coronary heart disease has currently become a hot topic. It is critical to build and select an appropriate animal model to successfully carry out relevant experimental research. This paper systematically summarizes the methods of constructing animal models of cognitive impairment secondary to coronary heart disease. It also combs the commonly used detection indicators and evaluation methods in order to provide a reference for the experimental study of cognitive impair-ment secondary to coronary heart disease.
format Article
id doaj-art-9777c037d5d84e1ba38e3bfdfd67f114
institution OA Journals
issn 1004-5511
language zho
publishDate 2022-08-01
publisher Editorial Office of New Medicine
record_format Article
series Yixue xinzhi zazhi
spelling doaj-art-9777c037d5d84e1ba38e3bfdfd67f1142025-08-20T02:35:29ZzhoEditorial Office of New MedicineYixue xinzhi zazhi1004-55112022-08-0132426026910.12173/j.issn.1004-5511.2022070166351Advances in animal models of cognitive impairment secondary to coronary heart diseaseQing WANGFeng-Lan LIUShi-Han XUYan-Fei LIUYue LIUFeng-Qin XUCoronary heart disease and cognitive impairment are both major diseases harmful to human health. A large number of studies have shown that coronary heart disease increases the risk of cognitive impairment in patients with the disease. It is of great clinical significance to explore the mechanism, prevention and treatment of such comorbidities. Research on the pathogenesis and treat-ment of cognitive impairment secondary to coronary heart disease has currently become a hot topic. It is critical to build and select an appropriate animal model to successfully carry out relevant experimental research. This paper systematically summarizes the methods of constructing animal models of cognitive impairment secondary to coronary heart disease. It also combs the commonly used detection indicators and evaluation methods in order to provide a reference for the experimental study of cognitive impair-ment secondary to coronary heart disease.https://yxxz.whuznhmedj.com/storage/attach/2208/kbjvB6edFl9GihAjing1HdocbISibmtTIEfcPnUZ.pdfcoronary heart disease cognitive impairment animal model
spellingShingle Qing WANG
Feng-Lan LIU
Shi-Han XU
Yan-Fei LIU
Yue LIU
Feng-Qin XU
Advances in animal models of cognitive impairment secondary to coronary heart disease
Yixue xinzhi zazhi
coronary heart disease
cognitive impairment
animal model
title Advances in animal models of cognitive impairment secondary to coronary heart disease
title_full Advances in animal models of cognitive impairment secondary to coronary heart disease
title_fullStr Advances in animal models of cognitive impairment secondary to coronary heart disease
title_full_unstemmed Advances in animal models of cognitive impairment secondary to coronary heart disease
title_short Advances in animal models of cognitive impairment secondary to coronary heart disease
title_sort advances in animal models of cognitive impairment secondary to coronary heart disease
topic coronary heart disease
cognitive impairment
animal model
url https://yxxz.whuznhmedj.com/storage/attach/2208/kbjvB6edFl9GihAjing1HdocbISibmtTIEfcPnUZ.pdf
work_keys_str_mv AT qingwang advancesinanimalmodelsofcognitiveimpairmentsecondarytocoronaryheartdisease
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AT shihanxu advancesinanimalmodelsofcognitiveimpairmentsecondarytocoronaryheartdisease
AT yanfeiliu advancesinanimalmodelsofcognitiveimpairmentsecondarytocoronaryheartdisease
AT yueliu advancesinanimalmodelsofcognitiveimpairmentsecondarytocoronaryheartdisease
AT fengqinxu advancesinanimalmodelsofcognitiveimpairmentsecondarytocoronaryheartdisease