A reduced peripapillary blood flow as a factor of primary open angle glaucoma development and progression
To assess the blood supply to the peripapillary area in patients with primary open-angle glaucoma (POAG) using optical coherence tomography with the function of amplitude decorrelation angiography (OCT-A). Material and Methods. 65 eyes of POAG patients (the main group) and 22 eyes of age-matched hea...
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Real Time Ltd
2018-10-01
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| Series: | Российский офтальмологический журнал |
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| Online Access: | https://roj.igb.ru/jour/article/view/40 |
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| author | N. I. Kurysheva E. V. Maslova A. V. Trubilina |
| author_facet | N. I. Kurysheva E. V. Maslova A. V. Trubilina |
| author_sort | N. I. Kurysheva |
| collection | DOAJ |
| description | To assess the blood supply to the peripapillary area in patients with primary open-angle glaucoma (POAG) using optical coherence tomography with the function of amplitude decorrelation angiography (OCT-A). Material and Methods. 65 eyes of POAG patients (the main group) and 22 eyes of age-matched healthy subjects (the control group) were examined. Spectral OCT (SD-OCT) technique with AngioVue OCT function was used to measure the average value of amplitude decorrelation (Peripapillary Flow Index), peripapillary vessel density, the parameters of the ganglion cell complex (GCC), including the focal loss volume (FLV) and the global loss volume (GLV), and the retinal nerve fiber layer (RNFL). Results. We revealed that blood flow reduction in the peripapillary retina, detected by OCT-A, precedes not only the functional but also the structural loss, determined by OCT and SAP. Conclusions. The new noninvasive technique for the examination of retinal blood flow, OCT-A, determines the reduction of hemoperfusion in peripapillary retina even at an early POAG stage and can serve as an important diagnostic method for early glaucoma detection // Russian Ophthalmological Journal, 2016; 3: 34-41. doi: 10.21516/2072-0076-2016-9-3-34-41. |
| format | Article |
| id | doaj-art-97747d96691442d4a6e7eb82012f11ed |
| institution | DOAJ |
| issn | 2072-0076 2587-5760 |
| language | Russian |
| publishDate | 2018-10-01 |
| publisher | Real Time Ltd |
| record_format | Article |
| series | Российский офтальмологический журнал |
| spelling | doaj-art-97747d96691442d4a6e7eb82012f11ed2025-08-20T03:19:23ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602018-10-0193344110.21516/2072-0076-2016-9-3-34-4140A reduced peripapillary blood flow as a factor of primary open angle glaucoma development and progressionN. I. Kurysheva0E. V. Maslova1A. V. Trubilina2Ophthalmological Center of the Federal Medical and Biological AgencyOphthalmological Center of the Federal Medical and Biological AgencyOphthalmological Center of the Federal Medical and Biological AgencyTo assess the blood supply to the peripapillary area in patients with primary open-angle glaucoma (POAG) using optical coherence tomography with the function of amplitude decorrelation angiography (OCT-A). Material and Methods. 65 eyes of POAG patients (the main group) and 22 eyes of age-matched healthy subjects (the control group) were examined. Spectral OCT (SD-OCT) technique with AngioVue OCT function was used to measure the average value of amplitude decorrelation (Peripapillary Flow Index), peripapillary vessel density, the parameters of the ganglion cell complex (GCC), including the focal loss volume (FLV) and the global loss volume (GLV), and the retinal nerve fiber layer (RNFL). Results. We revealed that blood flow reduction in the peripapillary retina, detected by OCT-A, precedes not only the functional but also the structural loss, determined by OCT and SAP. Conclusions. The new noninvasive technique for the examination of retinal blood flow, OCT-A, determines the reduction of hemoperfusion in peripapillary retina even at an early POAG stage and can serve as an important diagnostic method for early glaucoma detection // Russian Ophthalmological Journal, 2016; 3: 34-41. doi: 10.21516/2072-0076-2016-9-3-34-41.https://roj.igb.ru/jour/article/view/40окт-ангиографияпервичная открытоугольная глаукомаглазной кровотокструктурные и функциональные потериoptical coherence tomographyoct angiographyprimary open-angle glaucomaocular blood flowstructural and functional losses |
| spellingShingle | N. I. Kurysheva E. V. Maslova A. V. Trubilina A reduced peripapillary blood flow as a factor of primary open angle glaucoma development and progression Российский офтальмологический журнал окт-ангиография первичная открытоугольная глаукома глазной кровоток структурные и функциональные потери optical coherence tomography oct angiography primary open-angle glaucoma ocular blood flow structural and functional losses |
| title | A reduced peripapillary blood flow as a factor of primary open angle glaucoma development and progression |
| title_full | A reduced peripapillary blood flow as a factor of primary open angle glaucoma development and progression |
| title_fullStr | A reduced peripapillary blood flow as a factor of primary open angle glaucoma development and progression |
| title_full_unstemmed | A reduced peripapillary blood flow as a factor of primary open angle glaucoma development and progression |
| title_short | A reduced peripapillary blood flow as a factor of primary open angle glaucoma development and progression |
| title_sort | reduced peripapillary blood flow as a factor of primary open angle glaucoma development and progression |
| topic | окт-ангиография первичная открытоугольная глаукома глазной кровоток структурные и функциональные потери optical coherence tomography oct angiography primary open-angle glaucoma ocular blood flow structural and functional losses |
| url | https://roj.igb.ru/jour/article/view/40 |
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