Immunotherapy enhances the risk of tumor oxidative stress and metastasis in lung cancer with radiation pneumonitis

Immunotherapy enhances the risk of tumor oxidative stress and metastasis in lung cancer with radiation pneumonitis

Radiation pneumonitis (RP) is a prevalent complication associated with lung cancer radiotherapy; nonetheless, its effects on lung cancer immunotherapy and the underlying biological mechanisms remain inadequately elucidated. Utilizing mouse models of RP and orthotopically lung cancer, we witnessed im...

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Bibliographic Details
Main Authors: Ruidi Jiao, Wenbo Xu, Kunpeng Xu, Mingxia Zhang, Weilong Liu, Wei Jiang, Luhua Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
radiation pneumonitis
immunotherapy
metastasis
oxidative stress
lung cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1629170/full
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