A comparative study of four cell-free DNA assays for detecting circulating tumor DNA in early breast cancer

A comparative study of four cell-free DNA assays for detecting circulating tumor DNA in early breast cancer

Abstract Early prediction of the response to neoadjuvant chemotherapy (NAC) enables tailoring treatment strategies to the specific needs of individual breast cancer patients. Circulating tumor DNA (ctDNA) has shown to be a prognostic factor for response on NAC during treatment. However, at this poin...

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Main Authors: Charlotta V. Mulder, Elisabeth M. Jongbloed, Marte C. Liefaard, Stavros Makrodimitris, Daan M. Hazelaar, Corine M. Beaufort, Vanja de Weerd, Lennart Mulder, Carolien H.M. van Deurzen, Gabe S. Sonke, Agnes Jager, Saskia M. Wilting, John W.M. Martens, Maurice P.H.M. Jansen, Esther H. Lips
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Breast Cancer Research
Subjects:
Early breast cancer
Neoadjuvant treatment
Circulating tumor DNA
Online Access:https://doi.org/10.1186/s13058-025-02077-8
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