Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment
Aim. The aim of this study is to assess the therapeutic efficacy of alpha-lipoic acid in patients with type 2 diabetes mellitus (DM) and non-proliferativediabetic retinopathy. Materials and methods. 47 patients with mild to moderate non-proliferative diabetic retinopathy were included in this tria...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Endocrinology Research Centre
2011-12-01
|
| Series: | Сахарный диабет |
| Subjects: | |
| Online Access: | https://www.dia-endojournals.ru/jour/article/view/5823 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850254280348401664 |
|---|---|
| author | Tatiana Yul'evna Demidova Yulia Alexandrovna Trakhtenberg |
| author_facet | Tatiana Yul'evna Demidova Yulia Alexandrovna Trakhtenberg |
| author_sort | Tatiana Yul'evna Demidova |
| collection | DOAJ |
| description | Aim. The aim of this study is to assess the therapeutic efficacy of alpha-lipoic acid in patients with type 2 diabetes mellitus (DM) and non-proliferativediabetic retinopathy. Materials and methods. 47 patients with mild to moderate non-proliferative diabetic retinopathy were included in this trial. Dynamics of ophthalmologicparameters were assessed by means of stereoscopic photography of ocular fundus. Patients were examined every 6 months in order to registernew cases of clinically significant macular oedema. Results. During 24 months follow-up period, patients treated with 600 mg of alpha-lipoic acid showed stabilization in development of diabetic retinopathy.New cases of macular oedema, as well as transition into a more severe stage of retonopathy were less common in those patients. Vision andcontrast sensation also remained stable in the majority of participants from experimental group.Conclusions. 600 mg of alpha-lipoic acid may be recommended for patients with type 2 DM as part of complex therapy |
| format | Article |
| id | doaj-art-975df920f71a4061900734e8e10e8d96 |
| institution | OA Journals |
| issn | 2072-0351 2072-0378 |
| language | English |
| publishDate | 2011-12-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj-art-975df920f71a4061900734e8e10e8d962025-08-20T01:57:09ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782011-12-01144828610.14341/2072-0351-58235781Alpha-lipoic acid in non-proliferative diabetic retinopathy treatmentTatiana Yul'evna Demidova0Yulia Alexandrovna Trakhtenberg1Russian Medical Academy of Postgraduate Education, MoscowMedical Centre "Diagnost", MoscowAim. The aim of this study is to assess the therapeutic efficacy of alpha-lipoic acid in patients with type 2 diabetes mellitus (DM) and non-proliferativediabetic retinopathy. Materials and methods. 47 patients with mild to moderate non-proliferative diabetic retinopathy were included in this trial. Dynamics of ophthalmologicparameters were assessed by means of stereoscopic photography of ocular fundus. Patients were examined every 6 months in order to registernew cases of clinically significant macular oedema. Results. During 24 months follow-up period, patients treated with 600 mg of alpha-lipoic acid showed stabilization in development of diabetic retinopathy.New cases of macular oedema, as well as transition into a more severe stage of retonopathy were less common in those patients. Vision andcontrast sensation also remained stable in the majority of participants from experimental group.Conclusions. 600 mg of alpha-lipoic acid may be recommended for patients with type 2 DM as part of complex therapyhttps://www.dia-endojournals.ru/jour/article/view/5823diabetes mellituscomplicationsretinopathy |
| spellingShingle | Tatiana Yul'evna Demidova Yulia Alexandrovna Trakhtenberg Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment Сахарный диабет diabetes mellitus complications retinopathy |
| title | Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment |
| title_full | Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment |
| title_fullStr | Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment |
| title_full_unstemmed | Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment |
| title_short | Alpha-lipoic acid in non-proliferative diabetic retinopathy treatment |
| title_sort | alpha lipoic acid in non proliferative diabetic retinopathy treatment |
| topic | diabetes mellitus complications retinopathy |
| url | https://www.dia-endojournals.ru/jour/article/view/5823 |
| work_keys_str_mv | AT tatianayulevnademidova alphalipoicacidinnonproliferativediabeticretinopathytreatment AT yuliaalexandrovnatrakhtenberg alphalipoicacidinnonproliferativediabeticretinopathytreatment |