Intraocular Lymphoma or Infection? Subretinal Aspirate Confirms the Diagnosis

Purpose. To demonstrate the importance of subretinal biopsy to reach a diagnosis when vitreous biopsy is negative or inconclusive. Methods. A 54-year-old Caucasian gentleman presented with bilateral anterior uveitis at JCUH. He initially responded to topical steroids and dilating agents. Subsequentl...

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Main Authors: A. Saad, S. O. Salceanu, K. Oswal, A. Aboushrkh, D. Hamada
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2018/6437603
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author A. Saad
S. O. Salceanu
K. Oswal
A. Aboushrkh
D. Hamada
author_facet A. Saad
S. O. Salceanu
K. Oswal
A. Aboushrkh
D. Hamada
author_sort A. Saad
collection DOAJ
description Purpose. To demonstrate the importance of subretinal biopsy to reach a diagnosis when vitreous biopsy is negative or inconclusive. Methods. A 54-year-old Caucasian gentleman presented with bilateral anterior uveitis at JCUH. He initially responded to topical steroids and dilating agents. Subsequently he developed bilateral panuveitis and cataract with poor response to treatment. Detailed workup had been done to rule out infectious etiology. A suspicion of lymphoma was considered and vitreous biopsy sample was taken from one eye, which was inconclusive. Then, to help with definitive diagnosis vitreous sample, subretinal aspirate and retinal biopsy were taken. Results. Subretinal aspirate revealed Aspergillus niger. Treatment was initiated accordingly. Conclusions. Subretinal aspirate and retinal biopsy can help with diagnosis of unusual clinical panuveitis like presentation.
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institution Kabale University
issn 2090-6722
2090-6730
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Case Reports in Ophthalmological Medicine
spelling doaj-art-975b19206ef542e0a5a1e45f7a1e351c2025-02-03T01:22:38ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302018-01-01201810.1155/2018/64376036437603Intraocular Lymphoma or Infection? Subretinal Aspirate Confirms the DiagnosisA. Saad0S. O. Salceanu1K. Oswal2A. Aboushrkh3D. Hamada4James Cook University Hospital (JCUH), Middlesbrough, UKJames Cook University Hospital (JCUH), Middlesbrough, UKJames Cook University Hospital (JCUH), Middlesbrough, UKZagazig University, Zagazig, EgyptZagazig University, Zagazig, EgyptPurpose. To demonstrate the importance of subretinal biopsy to reach a diagnosis when vitreous biopsy is negative or inconclusive. Methods. A 54-year-old Caucasian gentleman presented with bilateral anterior uveitis at JCUH. He initially responded to topical steroids and dilating agents. Subsequently he developed bilateral panuveitis and cataract with poor response to treatment. Detailed workup had been done to rule out infectious etiology. A suspicion of lymphoma was considered and vitreous biopsy sample was taken from one eye, which was inconclusive. Then, to help with definitive diagnosis vitreous sample, subretinal aspirate and retinal biopsy were taken. Results. Subretinal aspirate revealed Aspergillus niger. Treatment was initiated accordingly. Conclusions. Subretinal aspirate and retinal biopsy can help with diagnosis of unusual clinical panuveitis like presentation.http://dx.doi.org/10.1155/2018/6437603
spellingShingle A. Saad
S. O. Salceanu
K. Oswal
A. Aboushrkh
D. Hamada
Intraocular Lymphoma or Infection? Subretinal Aspirate Confirms the Diagnosis
Case Reports in Ophthalmological Medicine
title Intraocular Lymphoma or Infection? Subretinal Aspirate Confirms the Diagnosis
title_full Intraocular Lymphoma or Infection? Subretinal Aspirate Confirms the Diagnosis
title_fullStr Intraocular Lymphoma or Infection? Subretinal Aspirate Confirms the Diagnosis
title_full_unstemmed Intraocular Lymphoma or Infection? Subretinal Aspirate Confirms the Diagnosis
title_short Intraocular Lymphoma or Infection? Subretinal Aspirate Confirms the Diagnosis
title_sort intraocular lymphoma or infection subretinal aspirate confirms the diagnosis
url http://dx.doi.org/10.1155/2018/6437603
work_keys_str_mv AT asaad intraocularlymphomaorinfectionsubretinalaspirateconfirmsthediagnosis
AT sosalceanu intraocularlymphomaorinfectionsubretinalaspirateconfirmsthediagnosis
AT koswal intraocularlymphomaorinfectionsubretinalaspirateconfirmsthediagnosis
AT aaboushrkh intraocularlymphomaorinfectionsubretinalaspirateconfirmsthediagnosis
AT dhamada intraocularlymphomaorinfectionsubretinalaspirateconfirmsthediagnosis