Polyethylene Glycol Electrolyte Lavage Solution versus Colonic Hydrotherapy for Bowel Preparation before Colonoscopy: A Single Center, Randomized, and Controlled Study

This single center, randomized, and controlled study aimed to compare the effectiveness and safety of polyethylene glycol electrolyte lavage (PEG-EL) solution and colonic hydrotherapy (CHT) for bowel preparation before colonoscopy. A total of 196 eligible outpatients scheduled for diagnostic colonos...

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Main Authors: Yan Cao, Kai-Yuan Zhang, Jiao Li, Hao Lu, Wan-Ling Xie, Sheng-Tao Liao, Dong-Feng Chen, Deng-Feng Zeng, Chun-Hui Lan
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2014/541586
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author Yan Cao
Kai-Yuan Zhang
Jiao Li
Hao Lu
Wan-Ling Xie
Sheng-Tao Liao
Dong-Feng Chen
Deng-Feng Zeng
Chun-Hui Lan
author_facet Yan Cao
Kai-Yuan Zhang
Jiao Li
Hao Lu
Wan-Ling Xie
Sheng-Tao Liao
Dong-Feng Chen
Deng-Feng Zeng
Chun-Hui Lan
author_sort Yan Cao
collection DOAJ
description This single center, randomized, and controlled study aimed to compare the effectiveness and safety of polyethylene glycol electrolyte lavage (PEG-EL) solution and colonic hydrotherapy (CHT) for bowel preparation before colonoscopy. A total of 196 eligible outpatients scheduled for diagnostic colonoscopy were randomly assigned to the PEG-EL (n=102) or CHT (n=94) groups. Primary outcome measures included colonic cleanliness and adverse effects. Secondary outcome measures were patient satisfaction and preference, colonoscopic findings, ileocecal arrival rate, examiner satisfaction, and cecal intubation time. The results show that PEG-EL group was associated with significantly better colonic cleanliness than CHT group, fewer adverse effects, and increased examiner satisfaction. However, the CHT group had higher patient satisfaction and higher diverticulosis detection rates. Moreover, the results showed the same ileocecal arrival rate and patient preference between the two groups (P>0.05). These findings indicate that PEG-EL is the preferred option in patients who followed the preparation instructions completely.
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institution Kabale University
issn 1687-6121
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language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Gastroenterology Research and Practice
spelling doaj-art-9746356d5935431dbb4ff299eee034a82025-08-20T03:37:09ZengWileyGastroenterology Research and Practice1687-61211687-630X2014-01-01201410.1155/2014/541586541586Polyethylene Glycol Electrolyte Lavage Solution versus Colonic Hydrotherapy for Bowel Preparation before Colonoscopy: A Single Center, Randomized, and Controlled StudyYan Cao0Kai-Yuan Zhang1Jiao Li2Hao Lu3Wan-Ling Xie4Sheng-Tao Liao5Dong-Feng Chen6Deng-Feng Zeng7Chun-Hui Lan8Department of Gastroenterology, Daping Hospital, The Third Military Medical University, 10 Changjiang Branch Road, Chongqing 400042, ChinaCadet Brigade, The Third Military Medical University, 30 Gaotanyan Street, Chongqing 400038, ChinaDepartment of Gastroenterology, Daping Hospital, The Third Military Medical University, 10 Changjiang Branch Road, Chongqing 400042, ChinaDepartment of Gastroenterology, Daping Hospital, The Third Military Medical University, 10 Changjiang Branch Road, Chongqing 400042, ChinaDepartment of Gastroenterology, Daping Hospital, The Third Military Medical University, 10 Changjiang Branch Road, Chongqing 400042, ChinaCadet Brigade, The Third Military Medical University, 30 Gaotanyan Street, Chongqing 400038, ChinaDepartment of Gastroenterology, Daping Hospital, The Third Military Medical University, 10 Changjiang Branch Road, Chongqing 400042, ChinaNursing Department, Daping Hospital, The Third Military Medical University, 10 Changjiang Branch Road, Chongqing 400042, ChinaDepartment of Gastroenterology, Daping Hospital, The Third Military Medical University, 10 Changjiang Branch Road, Chongqing 400042, ChinaThis single center, randomized, and controlled study aimed to compare the effectiveness and safety of polyethylene glycol electrolyte lavage (PEG-EL) solution and colonic hydrotherapy (CHT) for bowel preparation before colonoscopy. A total of 196 eligible outpatients scheduled for diagnostic colonoscopy were randomly assigned to the PEG-EL (n=102) or CHT (n=94) groups. Primary outcome measures included colonic cleanliness and adverse effects. Secondary outcome measures were patient satisfaction and preference, colonoscopic findings, ileocecal arrival rate, examiner satisfaction, and cecal intubation time. The results show that PEG-EL group was associated with significantly better colonic cleanliness than CHT group, fewer adverse effects, and increased examiner satisfaction. However, the CHT group had higher patient satisfaction and higher diverticulosis detection rates. Moreover, the results showed the same ileocecal arrival rate and patient preference between the two groups (P>0.05). These findings indicate that PEG-EL is the preferred option in patients who followed the preparation instructions completely.http://dx.doi.org/10.1155/2014/541586
spellingShingle Yan Cao
Kai-Yuan Zhang
Jiao Li
Hao Lu
Wan-Ling Xie
Sheng-Tao Liao
Dong-Feng Chen
Deng-Feng Zeng
Chun-Hui Lan
Polyethylene Glycol Electrolyte Lavage Solution versus Colonic Hydrotherapy for Bowel Preparation before Colonoscopy: A Single Center, Randomized, and Controlled Study
Gastroenterology Research and Practice
title Polyethylene Glycol Electrolyte Lavage Solution versus Colonic Hydrotherapy for Bowel Preparation before Colonoscopy: A Single Center, Randomized, and Controlled Study
title_full Polyethylene Glycol Electrolyte Lavage Solution versus Colonic Hydrotherapy for Bowel Preparation before Colonoscopy: A Single Center, Randomized, and Controlled Study
title_fullStr Polyethylene Glycol Electrolyte Lavage Solution versus Colonic Hydrotherapy for Bowel Preparation before Colonoscopy: A Single Center, Randomized, and Controlled Study
title_full_unstemmed Polyethylene Glycol Electrolyte Lavage Solution versus Colonic Hydrotherapy for Bowel Preparation before Colonoscopy: A Single Center, Randomized, and Controlled Study
title_short Polyethylene Glycol Electrolyte Lavage Solution versus Colonic Hydrotherapy for Bowel Preparation before Colonoscopy: A Single Center, Randomized, and Controlled Study
title_sort polyethylene glycol electrolyte lavage solution versus colonic hydrotherapy for bowel preparation before colonoscopy a single center randomized and controlled study
url http://dx.doi.org/10.1155/2014/541586
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