Targeting TRPM3 as a potential therapeutic approach for autosomal dominant polycystic kidney disease

Abstract Cystic diseases, especially autosomal dominant polycystic kidney disease (ADPKD; incidence approx. 1/1000), are a leading cause of renal failure, caused by appearance and growth of renal cysts that can lead to renal failure in middle age. Most ADPKD cases are caused by mutations in PKD1 or...

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Bibliographic Details
Main Authors: Hüseyin Gül, Jamie A. Davies
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-89200-z
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