Prediction of CD8+ T cell infiltration in the tumor microenvironment of HGSOC patients

Prediction of CD8+ T cell infiltration in the tumor microenvironment of HGSOC patients

Abstract The tumor microenvironment (TME), particularly CD8+ T cell infiltration, critically influences high-grade serous ovarian cancer (HGSOC) progression and treatment response. The development and management of cancer depend heavily on CD8+ T cells. Identifying non-invasive predictors of TME imm...

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Bibliographic Details
Main Authors: Jia Mai, Ling Yang, YuXin Chen, XiaoXu Zeng, HongJian Xie, XiaoJuan Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
High-grade serous ovarian cancer
CD8+ T cells
Tumor microenvironment
Peripheral blood parameters
Prognosis
Spatial distribution
Online Access:https://doi.org/10.1038/s41598-025-14720-7
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