Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices
The presence of tumor cells in bone marrow, peripheral blood and lymph nodes has proven its clinical and prognostic value. Since the frequency of these cells in bone marrow and blood is sometimes as low as 1 per million and due to the fact that for the analysis of lymph nodes many sectioning levels...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2006-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.1155/2006/610562 |
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| author | Wilma E. Mesker Hans Vrolijk Willem C. R. Sloos Rob A. E. M. Tollenaar Hans J. Tanke |
| author_facet | Wilma E. Mesker Hans Vrolijk Willem C. R. Sloos Rob A. E. M. Tollenaar Hans J. Tanke |
| author_sort | Wilma E. Mesker |
| collection | DOAJ |
| description | The presence of tumor cells in bone marrow, peripheral blood and lymph nodes has proven its clinical and prognostic value. Since the frequency of these cells in bone marrow and blood is sometimes as low as 1 per million and due to the fact that for the analysis of lymph nodes many sectioning levels have to be analyzed, automated imaging devices have been suggested as an useful alternative to conventional manual screening of specimens. The aim of this paper is to review the performance of current equipment that is commercially available, based on literature published so far. Requirements for introducing this equipment for routine clinical practice are discussed. |
| format | Article |
| id | doaj-art-973a8aa7d4704b73aec818f86c71a137 |
| institution | Kabale University |
| issn | 1570-5870 1875-8606 |
| language | English |
| publishDate | 2006-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cellular Oncology |
| spelling | doaj-art-973a8aa7d4704b73aec818f86c71a1372025-08-20T03:37:09ZengWileyCellular Oncology1570-58701875-86062006-01-0128414115010.1155/2006/610562Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging DevicesWilma E. Mesker0Hans Vrolijk1Willem C. R. Sloos2Rob A. E. M. Tollenaar3Hans J. Tanke4Department of Molecular Cell Biology, Leiden University Medical Center (LUMC), Leiden, The NetherlandsDepartment of Molecular Cell Biology, Leiden University Medical Center (LUMC), Leiden, The NetherlandsDepartment of Molecular Cell Biology, Leiden University Medical Center (LUMC), Leiden, The NetherlandsDepartment of Surgery, Leiden University Medical Center (LUMC), Leiden, The NetherlandsDepartment of Molecular Cell Biology, Leiden University Medical Center (LUMC), Leiden, The NetherlandsThe presence of tumor cells in bone marrow, peripheral blood and lymph nodes has proven its clinical and prognostic value. Since the frequency of these cells in bone marrow and blood is sometimes as low as 1 per million and due to the fact that for the analysis of lymph nodes many sectioning levels have to be analyzed, automated imaging devices have been suggested as an useful alternative to conventional manual screening of specimens. The aim of this paper is to review the performance of current equipment that is commercially available, based on literature published so far. Requirements for introducing this equipment for routine clinical practice are discussed.http://dx.doi.org/10.1155/2006/610562 |
| spellingShingle | Wilma E. Mesker Hans Vrolijk Willem C. R. Sloos Rob A. E. M. Tollenaar Hans J. Tanke Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices Cellular Oncology |
| title | Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices |
| title_full | Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices |
| title_fullStr | Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices |
| title_full_unstemmed | Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices |
| title_short | Detection of Tumor Cells in Bone Marrow, Peripheral Blood and Lymph Nodes by Automated Imaging Devices |
| title_sort | detection of tumor cells in bone marrow peripheral blood and lymph nodes by automated imaging devices |
| url | http://dx.doi.org/10.1155/2006/610562 |
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