LncRNA 4933431K23Rik modulate microglial phenotype via inhibiting miR-10a-5p in spinal cord injury induced neuropathic pain

LncRNA 4933431K23Rik modulate microglial phenotype via inhibiting miR-10a-5p in spinal cord injury induced neuropathic pain

Abstract Neuropathic pain (NP) is caused by primary damage and dysfunction of nervous system, in which spinal cord injury (SCI) is a common cause of NP. Evidence shows that neuroinflammation and oxidative stress are related to the pathophysiology of NP, in which the activation of microglia and astro...

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Bibliographic Details
Main Authors: Changhui You, Waiping Zhou, Ping Ye, Li Zhang, Wenchao Sun, Lili Tian, Bocheng Peng, Mengying Hu, Bo Xu
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
LncRNA4933431K23Rik
miR-10a-5p
Astrocytes
Spinal cord injury
Neuropathic pain
Online Access:https://doi.org/10.1038/s41598-025-91021-z
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