Candida albicans aspartyl protease (Sap6) inhibits neutrophil function via a “Trojan horse” mechanism

Abstract Candida albicans, a prevalent fungal pathogen, employs aspartyl proteases such as Sap6 to evade immune defenses, challenging our understanding of host‒pathogen interactions. This research examined the impact of Sap6 on neutrophil responses, which are crucial for innate immunity. Employing f...

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Bibliographic Details
Main Authors: Marcin Zawrotniak, Dorota Satala, Magdalena Juszczak, Grażyna Bras, Maria Rapala-Kozik
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-91425-x
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