Nucleus pulposus cell network modelling in the intervertebral disc

Nucleus pulposus cell network modelling in the intervertebral disc

Abstract Intervertebral disc degeneration (IDD) results from an imbalance between anabolic and catabolic processes in the extracellular matrix (ECM). Due to complex biochemical interactions, a comprehensive understanding is needed. This study presents a regulatory network model (RNM) for nucleus pul...

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Bibliographic Details
Main Authors: Sofia Tseranidou, Maria Segarra-Queralt, Francis Kiptengwer Chemorion, Christine Lyn Le Maitre, Janet Piñero, Jérôme Noailly
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-024-00479-6
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