Identification of immune and major depressive disorder-related diagnostic markers for early nonalcoholic fatty liver disease by WGCNA and machine learning

Identification of immune and major depressive disorder-related diagnostic markers for early nonalcoholic fatty liver disease by WGCNA and machine learning

BackgroundMajor depressive disorder (MDD) and nonalcoholic fatty liver disease (NAFLD) are highly prevalent conditions that exhibit significant pathophysiological overlap, particularly in metabolic and immune pathways.ObjectiveThis study aims to bridge this gap by integrating transcriptomic data fro...

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Bibliographic Details
Main Authors: Yuyun Jia, Yanping Cao, Qin Yin, Xueqian Li, Xiu Wen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Bioinformatics
Subjects:
major depressive disorder
nonalcoholic fatty liver disease
simple steatosis
nonalcoholic steatohepatitis
machine learning
weighted gene co-expression network analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2025.1594971/full
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