Using functional annotation for the empirical determination of Bayes Factors for genome-wide association study analysis.
A genome wide association study (GWAS) typically results in a few highly significant 'hits' and a much larger set of suggestive signals ('near-hits'). The latter group are expected to be a mixture of true and false associations. One promising strategy to help separate these is to...
Saved in:
| Main Authors: | Jo Knight, Michael R Barnes, Gerome Breen, Michael E Weale |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-04-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0014808&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
A Bayesian method to incorporate hundreds of functional characteristics with association evidence to improve variant prioritization.
by: Sarah A Gagliano, et al.
Published: (2014-01-01) -
Functional annotation of the animal genomes: An integrated annotation resource for the horse.
by: Sichong Peng, et al.
Published: (2023-03-01) -
Genome-Wide Association of Heroin Dependence in Han Chinese.
by: Gursharan Kalsi, et al.
Published: (2016-01-01) -
All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs.
by: Andrew J Schork, et al.
Published: (2013-04-01) -
Annotated Bioinformatic Pipelines for Genome Assembly and Annotation of Mitochondrial Genomes
by: Jessica Winn, et al.
Published: (2025-03-01)