Integrative analysis of SEPN1 in glioma: Prognostic roles, functional implications, and potential therapeutic interventions.

Integrative analysis of SEPN1 in glioma: Prognostic roles, functional implications, and potential therapeutic interventions.

<h4>Background</h4>SEPN1, a selenoprotein involved in redox regulation and endoplasmic reticulum stress response, has an unclear role in cancer. This study aims to investigate the expression, prognostic significance, and tumor microenvironment (TME) relevance of SEPN1 across pan-cancer,...

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Main Authors: Zisong Wang, Danwen Wang, Xuanyu Wang, Yihang Xu, Yunhe Yuan, Yuxin Chen, Zhiqiang Li, Xiaoping Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0318501
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