Dominant and cross-reactive S1-specific memory B cell response induced by primary SARS-CoV-2 infection

Dominant and cross-reactive S1-specific memory B cell response induced by primary SARS-CoV-2 infection

Abstract The protective component of specific memory B cells (MBCs) response relative to serum antibody response in primary SARS-CoV-2 infection is not well understood. Using a relatively unbiased B-cell culture method with a limited number of MBCs in each well (100 cells/well), we characterized the...

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Main Authors: Xiaomin Xing, Zhaoyong Zhang, Yingfen Wen, Wenjing Guo, Xulei Zhang, Yuyi Min, Kexin Zhong, Lu Zhang, Peilan Wei, Shengnan Zhang, Yuejun Pan, Yanqun Wang, Jincun Zhao, Yongjun Guan, Lei Yu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-06847-4
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