An association between average daily sleep duration and gallstones in US adults
Abstract Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of gallstones in adults has not been thoroughly investigated. This study analyzes data from 7,441 individuals from the NHANES 2017–2020 data...
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Nature Portfolio
2025-02-01
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Online Access: | https://doi.org/10.1038/s41598-025-89157-z |
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author | Yong Fang Qiuyuan Xu Jia Xu HaiHua Wang |
author_facet | Yong Fang Qiuyuan Xu Jia Xu HaiHua Wang |
author_sort | Yong Fang |
collection | DOAJ |
description | Abstract Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of gallstones in adults has not been thoroughly investigated. This study analyzes data from 7,441 individuals from the NHANES 2017–2020 dataset, using exclusion criteria to refine the participant pool. Employing multivariate logistic regression and subgroup analyses while controlling for potential confounders, we assessed the association between average daily sleep duration and the prevalence of gallstones. Our results revealed a statistically significant inverse association (OR = 0.92; 95% CI: 0.86, 0.99; p = 0.0236). This association was consistent across various demographic and health-related subgroups. Interestingly, the inflection points were observed among middle-aged adults (40–60 years) and individuals with diabetes. These findings could inform public health strategies on sleep management, potentially aiding in the prevention of gallstones within these populations. |
format | Article |
id | doaj-art-96f78922fbaa4f89b0437c9c61298e2d |
institution | Kabale University |
issn | 2045-2322 |
language | English |
publishDate | 2025-02-01 |
publisher | Nature Portfolio |
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spelling | doaj-art-96f78922fbaa4f89b0437c9c61298e2d2025-02-09T12:33:24ZengNature PortfolioScientific Reports2045-23222025-02-0115111010.1038/s41598-025-89157-zAn association between average daily sleep duration and gallstones in US adultsYong Fang0Qiuyuan Xu1Jia Xu2HaiHua Wang3Affiliated XiaoShan Hospital of WenZhou Medical University (XiaoShan District First People’s Hospital)Affiliated XiaoShan Hospital of WenZhou Medical University (XiaoShan District First People’s Hospital)Affiliated XiaoShan Hospital of WenZhou Medical University (XiaoShan District First People’s Hospital)Affiliated XiaoShan Hospital of WenZhou Medical University (XiaoShan District First People’s Hospital)Abstract Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of gallstones in adults has not been thoroughly investigated. This study analyzes data from 7,441 individuals from the NHANES 2017–2020 dataset, using exclusion criteria to refine the participant pool. Employing multivariate logistic regression and subgroup analyses while controlling for potential confounders, we assessed the association between average daily sleep duration and the prevalence of gallstones. Our results revealed a statistically significant inverse association (OR = 0.92; 95% CI: 0.86, 0.99; p = 0.0236). This association was consistent across various demographic and health-related subgroups. Interestingly, the inflection points were observed among middle-aged adults (40–60 years) and individuals with diabetes. These findings could inform public health strategies on sleep management, potentially aiding in the prevention of gallstones within these populations.https://doi.org/10.1038/s41598-025-89157-zAverage daily sleep durationGallstonesNHANESCross-sectional study |
spellingShingle | Yong Fang Qiuyuan Xu Jia Xu HaiHua Wang An association between average daily sleep duration and gallstones in US adults Scientific Reports Average daily sleep duration Gallstones NHANES Cross-sectional study |
title | An association between average daily sleep duration and gallstones in US adults |
title_full | An association between average daily sleep duration and gallstones in US adults |
title_fullStr | An association between average daily sleep duration and gallstones in US adults |
title_full_unstemmed | An association between average daily sleep duration and gallstones in US adults |
title_short | An association between average daily sleep duration and gallstones in US adults |
title_sort | association between average daily sleep duration and gallstones in us adults |
topic | Average daily sleep duration Gallstones NHANES Cross-sectional study |
url | https://doi.org/10.1038/s41598-025-89157-z |
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