An association between average daily sleep duration and gallstones in US adults

Abstract Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of gallstones in adults has not been thoroughly investigated. This study analyzes data from 7,441 individuals from the NHANES 2017–2020 data...

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Main Authors: Yong Fang, Qiuyuan Xu, Jia Xu, HaiHua Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-89157-z
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author Yong Fang
Qiuyuan Xu
Jia Xu
HaiHua Wang
author_facet Yong Fang
Qiuyuan Xu
Jia Xu
HaiHua Wang
author_sort Yong Fang
collection DOAJ
description Abstract Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of gallstones in adults has not been thoroughly investigated. This study analyzes data from 7,441 individuals from the NHANES 2017–2020 dataset, using exclusion criteria to refine the participant pool. Employing multivariate logistic regression and subgroup analyses while controlling for potential confounders, we assessed the association between average daily sleep duration and the prevalence of gallstones. Our results revealed a statistically significant inverse association (OR = 0.92; 95% CI: 0.86, 0.99; p = 0.0236). This association was consistent across various demographic and health-related subgroups. Interestingly, the inflection points were observed among middle-aged adults (40–60 years) and individuals with diabetes. These findings could inform public health strategies on sleep management, potentially aiding in the prevention of gallstones within these populations.
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spelling doaj-art-96f78922fbaa4f89b0437c9c61298e2d2025-02-09T12:33:24ZengNature PortfolioScientific Reports2045-23222025-02-0115111010.1038/s41598-025-89157-zAn association between average daily sleep duration and gallstones in US adultsYong Fang0Qiuyuan Xu1Jia Xu2HaiHua Wang3Affiliated XiaoShan Hospital of WenZhou Medical University (XiaoShan District First People’s Hospital)Affiliated XiaoShan Hospital of WenZhou Medical University (XiaoShan District First People’s Hospital)Affiliated XiaoShan Hospital of WenZhou Medical University (XiaoShan District First People’s Hospital)Affiliated XiaoShan Hospital of WenZhou Medical University (XiaoShan District First People’s Hospital)Abstract Despite extensive research on the impact of health factors and sleep, the specific association between average daily sleep duration and the prevalence of gallstones in adults has not been thoroughly investigated. This study analyzes data from 7,441 individuals from the NHANES 2017–2020 dataset, using exclusion criteria to refine the participant pool. Employing multivariate logistic regression and subgroup analyses while controlling for potential confounders, we assessed the association between average daily sleep duration and the prevalence of gallstones. Our results revealed a statistically significant inverse association (OR = 0.92; 95% CI: 0.86, 0.99; p = 0.0236). This association was consistent across various demographic and health-related subgroups. Interestingly, the inflection points were observed among middle-aged adults (40–60 years) and individuals with diabetes. These findings could inform public health strategies on sleep management, potentially aiding in the prevention of gallstones within these populations.https://doi.org/10.1038/s41598-025-89157-zAverage daily sleep durationGallstonesNHANESCross-sectional study
spellingShingle Yong Fang
Qiuyuan Xu
Jia Xu
HaiHua Wang
An association between average daily sleep duration and gallstones in US adults
Scientific Reports
Average daily sleep duration
Gallstones
NHANES
Cross-sectional study
title An association between average daily sleep duration and gallstones in US adults
title_full An association between average daily sleep duration and gallstones in US adults
title_fullStr An association between average daily sleep duration and gallstones in US adults
title_full_unstemmed An association between average daily sleep duration and gallstones in US adults
title_short An association between average daily sleep duration and gallstones in US adults
title_sort association between average daily sleep duration and gallstones in us adults
topic Average daily sleep duration
Gallstones
NHANES
Cross-sectional study
url https://doi.org/10.1038/s41598-025-89157-z
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