A study to correlate trends in perfusion index and bispectral index for assessment of depth of anesthesia: A cross-sectional study

Background: Accurate anesthesia depth monitoring is crucial for patient safety. Bispectral index (BIS) measures brain activity, whereas perfusion index (PI) reflects peripheral blood flow and sympathetic tone. BIS is a gold standard but is limited by cost and interference, whereas PI is a simpler, m...

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Main Authors: Karthik Raj M, Shalini Jain, Manish Banjare, Nidhi Sharma
Format: Article
Language:English
Published: Manipal College of Medical Sciences, Pokhara 2025-05-01
Series:Asian Journal of Medical Sciences
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Online Access:https://ajmsjournal.info/index.php/AJMS/article/view/4465
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author Karthik Raj M
Shalini Jain
Manish Banjare
Nidhi Sharma
author_facet Karthik Raj M
Shalini Jain
Manish Banjare
Nidhi Sharma
author_sort Karthik Raj M
collection DOAJ
description Background: Accurate anesthesia depth monitoring is crucial for patient safety. Bispectral index (BIS) measures brain activity, whereas perfusion index (PI) reflects peripheral blood flow and sympathetic tone. BIS is a gold standard but is limited by cost and interference, whereas PI is a simpler, more accessible alternative. Aims and Objectives: This study aimed to correlate trends in PI and BIS for assessing anesthesia depth. The primary objective was to examine the correlation between PI and BIS trends. The secondary objective was to monitor intraoperative hemodynamic fluctuations and their relationship with PI and BIS. Materials and Methods: A cross-sectional study was conducted over 12 months at M.G.M. Medical College and M.Y. Hospital, Indore. Seventy patients (18–65 years, the American Society of Anesthesiologists physical status 1 or 2) undergoing elective surgery under general anesthesia were enrolled in the study. Exclusion criteria included cardiovascular, neurological, psychiatric disorders, and peripheral vascular diseases. BIS and PI were monitored throughout the perioperative period. Statistical analysis was done using IBM SPSS Version 22, with significance set at P<0.05. Results: A strong negative correlation between BIS and PI (P<0.05) was found. BIS also showed negative correlations with heart rate, systolic, and diastolic blood pressure (P<0.05). PI had a significant positive correlation with heart rate (P<0.05) and a negative correlation with blood pressure (P<0.05). Conclusion: The significant negative correlation between BIS and PI supports PI as a potential alternative for anesthesia depth monitoring, especially in resource-limited settings.
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spelling doaj-art-96ea93d6e76b49fd998b87cd0c9e077b2025-08-20T02:20:33ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762025-05-011652126https://doi.org/10.71152/ajms.v16i5.4465A study to correlate trends in perfusion index and bispectral index for assessment of depth of anesthesia: A cross-sectional studyKarthik Raj M 0https://orcid.org/0009-0001-6546-5090Shalini Jain 1https://orcid.org/0000-0001-6702-9666Manish Banjare 2https://orcid.org/0000-0001-7695-5645Nidhi Sharma 3https://orcid.org/0009-0009-5675-8842Postgraduate Resident, Department of Anesthesia, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India Professor, Department of Anesthesia, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India Professor and Head, Department of Anesthesia, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India Assistant Professor, Department of Anesthesia, M.G.M. Medical College and M.Y. Hospital, Indore, Madhya Pradesh, India Background: Accurate anesthesia depth monitoring is crucial for patient safety. Bispectral index (BIS) measures brain activity, whereas perfusion index (PI) reflects peripheral blood flow and sympathetic tone. BIS is a gold standard but is limited by cost and interference, whereas PI is a simpler, more accessible alternative. Aims and Objectives: This study aimed to correlate trends in PI and BIS for assessing anesthesia depth. The primary objective was to examine the correlation between PI and BIS trends. The secondary objective was to monitor intraoperative hemodynamic fluctuations and their relationship with PI and BIS. Materials and Methods: A cross-sectional study was conducted over 12 months at M.G.M. Medical College and M.Y. Hospital, Indore. Seventy patients (18–65 years, the American Society of Anesthesiologists physical status 1 or 2) undergoing elective surgery under general anesthesia were enrolled in the study. Exclusion criteria included cardiovascular, neurological, psychiatric disorders, and peripheral vascular diseases. BIS and PI were monitored throughout the perioperative period. Statistical analysis was done using IBM SPSS Version 22, with significance set at P<0.05. Results: A strong negative correlation between BIS and PI (P<0.05) was found. BIS also showed negative correlations with heart rate, systolic, and diastolic blood pressure (P<0.05). PI had a significant positive correlation with heart rate (P<0.05) and a negative correlation with blood pressure (P<0.05). Conclusion: The significant negative correlation between BIS and PI supports PI as a potential alternative for anesthesia depth monitoring, especially in resource-limited settings.https://ajmsjournal.info/index.php/AJMS/article/view/4465anesthesia depth; bispectral index; perfusion index; intraoperative hemodynamics; heart rate; blood pressure; systolic blood pressure; diastolic blood pressure; general anesthesia; anesthesia monitoring; hemodynamic parameters; portable monitoring tools
spellingShingle Karthik Raj M
Shalini Jain
Manish Banjare
Nidhi Sharma
A study to correlate trends in perfusion index and bispectral index for assessment of depth of anesthesia: A cross-sectional study
Asian Journal of Medical Sciences
anesthesia depth; bispectral index; perfusion index; intraoperative hemodynamics; heart rate; blood pressure; systolic blood pressure; diastolic blood pressure; general anesthesia; anesthesia monitoring; hemodynamic parameters; portable monitoring tools
title A study to correlate trends in perfusion index and bispectral index for assessment of depth of anesthesia: A cross-sectional study
title_full A study to correlate trends in perfusion index and bispectral index for assessment of depth of anesthesia: A cross-sectional study
title_fullStr A study to correlate trends in perfusion index and bispectral index for assessment of depth of anesthesia: A cross-sectional study
title_full_unstemmed A study to correlate trends in perfusion index and bispectral index for assessment of depth of anesthesia: A cross-sectional study
title_short A study to correlate trends in perfusion index and bispectral index for assessment of depth of anesthesia: A cross-sectional study
title_sort study to correlate trends in perfusion index and bispectral index for assessment of depth of anesthesia a cross sectional study
topic anesthesia depth; bispectral index; perfusion index; intraoperative hemodynamics; heart rate; blood pressure; systolic blood pressure; diastolic blood pressure; general anesthesia; anesthesia monitoring; hemodynamic parameters; portable monitoring tools
url https://ajmsjournal.info/index.php/AJMS/article/view/4465
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