Dexmedetomidine Pharmacokinetics in Neonates with Hypoxic-Ischemic Encephalopathy Receiving Hypothermia
Dexmedetomidine is a promising sedative and analgesic for newborns with hypoxic-ischemic encephalopathy (HIE) undergoing therapeutic hypothermia (TH). Pharmacokinetics and safety of dexmedetomidine were evaluated in a phase I, single-center, open-label study to inform future trial strategies. We rec...
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| Main Authors: | Ryan M. McAdams, Daniel Pak, Bojan Lalovic, Brian Phillips, Danny D. Shen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
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| Series: | Anesthesiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2020/2582965 |
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