Prolonged survival by combination treatment with a standardized herbal extract from Japanese Kampo-medicine (Juzentaihoto) and gemcitabine in an orthotopic transplantation pancreatic cancer model

Prolonged survival by combination treatment with a standardized herbal extract from Japanese Kampo-medicine (Juzentaihoto) and gemcitabine in an orthotopic transplantation pancreatic cancer model

Pancreatic ductal adenocarcinoma (PDAC) is characterized by its poor prognosis. Traditional Japanese herbal medicine (Kampo), such as Juzentaihoto (a standardized combination of 10 herbal extracts), has shown immune modulatory effects, modulation of microcirculation, and amelioration of fatigue. It...

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Bibliographic Details
Main Authors: Joanna Napp, Paulina Siebel, Hans Rausch, Kenny Kuchta, Thomas Efferth, Frauke Alves, Volker Ellenrieder, Silke Cameron
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Oncology
Subjects:
Kampo medicine
Juzentaihoto
gemcitabine
pancreatic ductal adenocarcinoma (PDAC)
orthotopic transplantation PDAC mouse model
murine KPC pancreatic tumor cells
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1454291/full
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