ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION

Aim. The assessment of cardiac hemodynamics in the test with reactive hyperemia in young females with idiopathic arterial hypotension.Material and methods. The comparative analysis was done, of echocardiography in the standard test with reactive hyperemia within brachial area among 72 women with idi...

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Main Authors: V. M. Baev, T. Yu. Agafonova, O. A. Samsonova, R. Sh. Dusakova
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2017-10-01
Series:Кардиоваскулярная терапия и профилактика
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Online Access:https://cardiovascular.elpub.ru/jour/article/view/555
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author V. M. Baev
T. Yu. Agafonova
O. A. Samsonova
R. Sh. Dusakova
author_facet V. M. Baev
T. Yu. Agafonova
O. A. Samsonova
R. Sh. Dusakova
author_sort V. M. Baev
collection DOAJ
description Aim. The assessment of cardiac hemodynamics in the test with reactive hyperemia in young females with idiopathic arterial hypotension.Material and methods. The comparative analysis was done, of echocardiography in the standard test with reactive hyperemia within brachial area among 72 women with idiopathic arterial hypotension — systolic blood pressure 94-98 mmHg, and in 37 females normotensive — systolic BP 120-123 mmHg. In both groups the age was 19 (18-22) y.o.Results. Reactive hyperemia in hypotension is followed by a significant increase of maximum velocities relation of the early (peak E) and delayed (peak A) diastolic filling of the left ventricle by 18%. In normotensive women there was no such change of the relation.Conclusion. In young females with idiopathic arterial hypotension the test with reactive hyperemia, as a model of acute hypoxia, is followed by isolated diastolic dysfunction of myocardium. Probably, it is related to the increase of the rate of already existing hypernitricoxidemia, which is a key factors for arterial hypotension pathogenesis.
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institution Kabale University
issn 1728-8800
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language Russian
publishDate 2017-10-01
publisher «SILICEA-POLIGRAF» LLC
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series Кардиоваскулярная терапия и профилактика
spelling doaj-art-96c8cffcb9304ed784a998baa9ab3c7e2025-08-20T03:35:47Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252017-10-01165161910.15829/1728-8800-2017-5-16-19480ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSIONV. M. Baev0T. Yu. Agafonova1O. A. Samsonova2R. Sh. Dusakova3Wagner E.A. Perm State Medical University of the Ministry of HealthWagner E.A. Perm State Medical University of the Ministry of HealthWagner E.A. Perm State Medical University of the Ministry of HealthWagner E.A. Perm State Medical University of the Ministry of HealthAim. The assessment of cardiac hemodynamics in the test with reactive hyperemia in young females with idiopathic arterial hypotension.Material and methods. The comparative analysis was done, of echocardiography in the standard test with reactive hyperemia within brachial area among 72 women with idiopathic arterial hypotension — systolic blood pressure 94-98 mmHg, and in 37 females normotensive — systolic BP 120-123 mmHg. In both groups the age was 19 (18-22) y.o.Results. Reactive hyperemia in hypotension is followed by a significant increase of maximum velocities relation of the early (peak E) and delayed (peak A) diastolic filling of the left ventricle by 18%. In normotensive women there was no such change of the relation.Conclusion. In young females with idiopathic arterial hypotension the test with reactive hyperemia, as a model of acute hypoxia, is followed by isolated diastolic dysfunction of myocardium. Probably, it is related to the increase of the rate of already existing hypernitricoxidemia, which is a key factors for arterial hypotension pathogenesis.https://cardiovascular.elpub.ru/jour/article/view/555arterial hypotensionhypernitricoxidemiaisolated diastolic dysfunction
spellingShingle V. M. Baev
T. Yu. Agafonova
O. A. Samsonova
R. Sh. Dusakova
ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION
Кардиоваскулярная терапия и профилактика
arterial hypotension
hypernitricoxidemia
isolated diastolic dysfunction
title ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION
title_full ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION
title_fullStr ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION
title_full_unstemmed ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION
title_short ISOLATED DIASTOLIC DYSFUNCTION AS A RESULT OF HYPERNITRICOXIDEMIA IN ARTERIAL HYPOTENSION
title_sort isolated diastolic dysfunction as a result of hypernitricoxidemia in arterial hypotension
topic arterial hypotension
hypernitricoxidemia
isolated diastolic dysfunction
url https://cardiovascular.elpub.ru/jour/article/view/555
work_keys_str_mv AT vmbaev isolateddiastolicdysfunctionasaresultofhypernitricoxidemiainarterialhypotension
AT tyuagafonova isolateddiastolicdysfunctionasaresultofhypernitricoxidemiainarterialhypotension
AT oasamsonova isolateddiastolicdysfunctionasaresultofhypernitricoxidemiainarterialhypotension
AT rshdusakova isolateddiastolicdysfunctionasaresultofhypernitricoxidemiainarterialhypotension