Disrupting HBV Persistence: Genetic Engineering Approach to Break the Oncogenic HBx Gene
Chronic Hepatitis B virus (HBV) infection can cause liver cirrhosis or cancer , making it a persistent worldwide health concern. Nucleoside analogs used in current antiviral treatments can prevent HBV from replicating, but they do not break the covalently closed circular DNA that HBV currently poss...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
National University of Sciences and Technology, Islamabad
2025-08-01
|
| Series: | NUST Journal of Engineering Sciences |
| Online Access: | https://journals.nust.edu.pk/index.php/njes/article/view/912 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849330539223318528 |
|---|---|
| author | Saleha Resham Haiqa Khan Fazal Adnan Sobia Manzoor |
| author_facet | Saleha Resham Haiqa Khan Fazal Adnan Sobia Manzoor |
| author_sort | Saleha Resham |
| collection | DOAJ |
| description |
Chronic Hepatitis B virus (HBV) infection can cause liver cirrhosis or cancer , making it a persistent worldwide health concern. Nucleoside analogs used in current antiviral treatments can prevent HBV from replicating, but they do not break the covalently closed circular DNA that HBV currently possesses.
|
| format | Article |
| id | doaj-art-96bef7c541644dc4a00bca3b4b68e143 |
| institution | Kabale University |
| issn | 2070-9900 2411-6319 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | National University of Sciences and Technology, Islamabad |
| record_format | Article |
| series | NUST Journal of Engineering Sciences |
| spelling | doaj-art-96bef7c541644dc4a00bca3b4b68e1432025-08-20T03:46:53ZengNational University of Sciences and Technology, IslamabadNUST Journal of Engineering Sciences2070-99002411-63192025-08-0118110.24949/njes.v18i1.912Disrupting HBV Persistence: Genetic Engineering Approach to Break the Oncogenic HBx GeneSaleha Resham0Haiqa Khan1Fazal Adnan2Sobia Manzoor3Atta ur Rahman School of Applied Biosciences, National University of Science and Technology (NUST)Atta ur Rahman School of Applied Biosciences, National University of Science and Technology (NUST)Atta ur Rahman School of Applied Biosciences, National University of Science and Technology (NUST)Atta ur Rahman School of Applied Biosciences, National University of Science and Technology (NUST) Chronic Hepatitis B virus (HBV) infection can cause liver cirrhosis or cancer , making it a persistent worldwide health concern. Nucleoside analogs used in current antiviral treatments can prevent HBV from replicating, but they do not break the covalently closed circular DNA that HBV currently possesses. https://journals.nust.edu.pk/index.php/njes/article/view/912 |
| spellingShingle | Saleha Resham Haiqa Khan Fazal Adnan Sobia Manzoor Disrupting HBV Persistence: Genetic Engineering Approach to Break the Oncogenic HBx Gene NUST Journal of Engineering Sciences |
| title | Disrupting HBV Persistence: Genetic Engineering Approach to Break the Oncogenic HBx Gene |
| title_full | Disrupting HBV Persistence: Genetic Engineering Approach to Break the Oncogenic HBx Gene |
| title_fullStr | Disrupting HBV Persistence: Genetic Engineering Approach to Break the Oncogenic HBx Gene |
| title_full_unstemmed | Disrupting HBV Persistence: Genetic Engineering Approach to Break the Oncogenic HBx Gene |
| title_short | Disrupting HBV Persistence: Genetic Engineering Approach to Break the Oncogenic HBx Gene |
| title_sort | disrupting hbv persistence genetic engineering approach to break the oncogenic hbx gene |
| url | https://journals.nust.edu.pk/index.php/njes/article/view/912 |
| work_keys_str_mv | AT saleharesham disruptinghbvpersistencegeneticengineeringapproachtobreaktheoncogenichbxgene AT haiqakhan disruptinghbvpersistencegeneticengineeringapproachtobreaktheoncogenichbxgene AT fazaladnan disruptinghbvpersistencegeneticengineeringapproachtobreaktheoncogenichbxgene AT sobiamanzoor disruptinghbvpersistencegeneticengineeringapproachtobreaktheoncogenichbxgene |