Duodenal coupling of pancreatic exocrine secretion and evacuatory activity of gastroduodenal complex
The aim of review. To present experimental and clinical data on enzyme-ergic regulatory coupling of exocrine pancreatic secretion and evacuatory activity of gastroduodenal complex.Original positions. Intraduodenal injection of pancreatin or trypsin as model of exocrine pancreatic secretion of enzyme...
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| Format: | Article |
| Language: | Russian |
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Gastro LLC
2011-05-01
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| Series: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
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| Online Access: | https://www.gastro-j.ru/jour/article/view/1405 |
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| _version_ | 1823860214737141760 |
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| author | G. F. Korot'ko |
| author_facet | G. F. Korot'ko |
| author_sort | G. F. Korot'ko |
| collection | DOAJ |
| description | The aim of review. To present experimental and clinical data on enzyme-ergic regulatory coupling of exocrine pancreatic secretion and evacuatory activity of gastroduodenal complex.Original positions. Intraduodenal injection of pancreatin or trypsin as model of exocrine pancreatic secretion of enzymes accelerates gastric evacuation of chymus to the duodenum and decreases pancreatic secretion in dose-dependant w ay. Both effects result from inhibition of endogenous cholecystokinin release which is the main stimulant of pancreatic enzymes secretion and inhibitor of gastric evacuation, suppressing antral motility, reducing brake efficacy of duodenoantral reflux.Conclusion. Enzymatic, acid-base and nutrient properties of duodenal chymus link parameters of pancreatic exocrine secretion and gastroduodenal evacuatory activity. |
| format | Article |
| id | doaj-art-96bdf0aa370845728c73d1aff5961391 |
| institution | Kabale University |
| issn | 1382-4376 2658-6673 |
| language | Russian |
| publishDate | 2011-05-01 |
| publisher | Gastro LLC |
| record_format | Article |
| series | Российский журнал гастроэнтерологии, гепатологии, колопроктологии |
| spelling | doaj-art-96bdf0aa370845728c73d1aff59613912025-02-10T16:14:31ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732011-05-012131318953Duodenal coupling of pancreatic exocrine secretion and evacuatory activity of gastroduodenal complexG. F. Korot'koThe aim of review. To present experimental and clinical data on enzyme-ergic regulatory coupling of exocrine pancreatic secretion and evacuatory activity of gastroduodenal complex.Original positions. Intraduodenal injection of pancreatin or trypsin as model of exocrine pancreatic secretion of enzymes accelerates gastric evacuation of chymus to the duodenum and decreases pancreatic secretion in dose-dependant w ay. Both effects result from inhibition of endogenous cholecystokinin release which is the main stimulant of pancreatic enzymes secretion and inhibitor of gastric evacuation, suppressing antral motility, reducing brake efficacy of duodenoantral reflux.Conclusion. Enzymatic, acid-base and nutrient properties of duodenal chymus link parameters of pancreatic exocrine secretion and gastroduodenal evacuatory activity.https://www.gastro-j.ru/jour/article/view/1405pancreassecretionevacuation of gastric contentspancreatinchronic pancreatitis |
| spellingShingle | G. F. Korot'ko Duodenal coupling of pancreatic exocrine secretion and evacuatory activity of gastroduodenal complex Российский журнал гастроэнтерологии, гепатологии, колопроктологии pancreas secretion evacuation of gastric contents pancreatin chronic pancreatitis |
| title | Duodenal coupling of pancreatic exocrine secretion and evacuatory activity of gastroduodenal complex |
| title_full | Duodenal coupling of pancreatic exocrine secretion and evacuatory activity of gastroduodenal complex |
| title_fullStr | Duodenal coupling of pancreatic exocrine secretion and evacuatory activity of gastroduodenal complex |
| title_full_unstemmed | Duodenal coupling of pancreatic exocrine secretion and evacuatory activity of gastroduodenal complex |
| title_short | Duodenal coupling of pancreatic exocrine secretion and evacuatory activity of gastroduodenal complex |
| title_sort | duodenal coupling of pancreatic exocrine secretion and evacuatory activity of gastroduodenal complex |
| topic | pancreas secretion evacuation of gastric contents pancreatin chronic pancreatitis |
| url | https://www.gastro-j.ru/jour/article/view/1405 |
| work_keys_str_mv | AT gfkorotko duodenalcouplingofpancreaticexocrinesecretionandevacuatoryactivityofgastroduodenalcomplex |