Preliminary application of the Sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unit
Abstract Background This study investigated the application of software-based data monitoring for quality control (QC) in continuous renal replacement therapy (CRRT) management. Methods This single-center pre-post intervention study, conducted in three ICUs of a tertiary hospital in Shanghai, compar...
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BMC
2025-08-01
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| Series: | Journal of Intensive Care |
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| Online Access: | https://doi.org/10.1186/s40560-025-00818-7 |
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| author | Wensan Wu Jianli Wang Chen Chen Junqi Feng Shuyi Zhang An Shi Jing Zhang Xinyi He Jiangchen Peng Mingli Zhu |
| author_facet | Wensan Wu Jianli Wang Chen Chen Junqi Feng Shuyi Zhang An Shi Jing Zhang Xinyi He Jiangchen Peng Mingli Zhu |
| author_sort | Wensan Wu |
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| description | Abstract Background This study investigated the application of software-based data monitoring for quality control (QC) in continuous renal replacement therapy (CRRT) management. Methods This single-center pre-post intervention study, conducted in three ICUs of a tertiary hospital in Shanghai, compared outcomes before (Jan–Dec 2023) and after (Jan–Dec 2024) implementing the Sharesource Connect system. Data from 9 Prismaflex CRRT machines were collected retrospectively during 2023 and prospectively on a monthly basis during 2024. Alongside the software, a comprehensive quality improvement program: (1) multidisciplinary team collaboration; (2) data-driven QC; and (3) structured training. Primary outcomes—filter lifespan, downtime percentage, delivered/prescribed dose ratio, ultrafiltration volume, and vascular access alarms—were compared. Results A total of 798 filters from 514 patients (2023) and 717 filters from 492 patients (2024) were analyzed. Key quality metrics improved significantly following implementation (2024 vs. 2023): Filter lifespan increased significantly from 20.08 ± 4.12 h to 24.08 ± 4.27 h (P = 0.043), Kaplan–Meier analysis demonstrated improved filter survival (Log-Rank p < 0.001). Cumulative survival increased from 2023 to 2024 at key time points: 12 h (69.1%–87.2%, + 18.1%), 24 h (30.9%–34.6%, + 3.7%), and 36 h (5.6%–13.6%, + 8.0%), with consistent improvements observed. Downtime percentage decreased from 39 to 28% (P = 0.015), reducing non-effective treatment time by 11 percentage points. The delivered/prescribed dose ratio increased from 82 to 86% (P = 0.046). The mean delivered dose was 35.67 ± 4.01 mL/kg/h (prescribed: 41.33 ± 4.5 mL/kg/h). Ultrafiltration volume remained stable (3.13 ± 0.37 vs. 3.52 ± 0.44 L/treatment day, P = 0.058). There was no significant difference in vascular access alarms (3.39 ± 1.44 vs. 2.93 ± 0.73 events/day, P = 0.392). Conclusion The Sharesource Connect system could be used for the monitoring, collection, and analysis of CRRT data to assist in the QC management related to CRRT, so as to provide a software basis for further multi-center studies or random control trials on the intelligent management of critical patients undergoing CRRT. |
| format | Article |
| id | doaj-art-96b95cd0d2194ee1baf00496b343959a |
| institution | Kabale University |
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| publishDate | 2025-08-01 |
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| spelling | doaj-art-96b95cd0d2194ee1baf00496b343959a2025-08-20T03:46:54ZengBMCJournal of Intensive Care2052-04922025-08-0113111110.1186/s40560-025-00818-7Preliminary application of the Sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unitWensan Wu0Jianli Wang1Chen Chen2Junqi Feng3Shuyi Zhang4An Shi5Jing Zhang6Xinyi He7Jiangchen Peng8Mingli Zhu9Department of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Medical Equipment, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Medical Equipment, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong UniversityAbstract Background This study investigated the application of software-based data monitoring for quality control (QC) in continuous renal replacement therapy (CRRT) management. Methods This single-center pre-post intervention study, conducted in three ICUs of a tertiary hospital in Shanghai, compared outcomes before (Jan–Dec 2023) and after (Jan–Dec 2024) implementing the Sharesource Connect system. Data from 9 Prismaflex CRRT machines were collected retrospectively during 2023 and prospectively on a monthly basis during 2024. Alongside the software, a comprehensive quality improvement program: (1) multidisciplinary team collaboration; (2) data-driven QC; and (3) structured training. Primary outcomes—filter lifespan, downtime percentage, delivered/prescribed dose ratio, ultrafiltration volume, and vascular access alarms—were compared. Results A total of 798 filters from 514 patients (2023) and 717 filters from 492 patients (2024) were analyzed. Key quality metrics improved significantly following implementation (2024 vs. 2023): Filter lifespan increased significantly from 20.08 ± 4.12 h to 24.08 ± 4.27 h (P = 0.043), Kaplan–Meier analysis demonstrated improved filter survival (Log-Rank p < 0.001). Cumulative survival increased from 2023 to 2024 at key time points: 12 h (69.1%–87.2%, + 18.1%), 24 h (30.9%–34.6%, + 3.7%), and 36 h (5.6%–13.6%, + 8.0%), with consistent improvements observed. Downtime percentage decreased from 39 to 28% (P = 0.015), reducing non-effective treatment time by 11 percentage points. The delivered/prescribed dose ratio increased from 82 to 86% (P = 0.046). The mean delivered dose was 35.67 ± 4.01 mL/kg/h (prescribed: 41.33 ± 4.5 mL/kg/h). Ultrafiltration volume remained stable (3.13 ± 0.37 vs. 3.52 ± 0.44 L/treatment day, P = 0.058). There was no significant difference in vascular access alarms (3.39 ± 1.44 vs. 2.93 ± 0.73 events/day, P = 0.392). Conclusion The Sharesource Connect system could be used for the monitoring, collection, and analysis of CRRT data to assist in the QC management related to CRRT, so as to provide a software basis for further multi-center studies or random control trials on the intelligent management of critical patients undergoing CRRT.https://doi.org/10.1186/s40560-025-00818-7Continuous renal replacement therapyQuality controlSoftwareIntelligent management |
| spellingShingle | Wensan Wu Jianli Wang Chen Chen Junqi Feng Shuyi Zhang An Shi Jing Zhang Xinyi He Jiangchen Peng Mingli Zhu Preliminary application of the Sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unit Journal of Intensive Care Continuous renal replacement therapy Quality control Software Intelligent management |
| title | Preliminary application of the Sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unit |
| title_full | Preliminary application of the Sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unit |
| title_fullStr | Preliminary application of the Sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unit |
| title_full_unstemmed | Preliminary application of the Sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unit |
| title_short | Preliminary application of the Sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unit |
| title_sort | preliminary application of the sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unit |
| topic | Continuous renal replacement therapy Quality control Software Intelligent management |
| url | https://doi.org/10.1186/s40560-025-00818-7 |
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