Copy number amplification of FLAD1 promotes the progression of triple-negative breast cancer through lipid metabolism

Copy number amplification of FLAD1 promotes the progression of triple-negative breast cancer through lipid metabolism

Abstract Triple-negative breast cancer (TNBC) is known for frequent copy number alterations (CNAs) and metabolic reprogramming. However, the mechanism by which CNAs of metabolic genes drive distinct metabolic reprogramming and affect disease progression remains unclear. Through an integrated analysi...

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Bibliographic Details
Main Authors: Xiao-Qing Song, Tian-Jian Yu, Yang Ou-Yang, Jia-Han Ding, Yi-Zhou Jiang, Zhi-Ming Shao, Yi Xiao
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56458-w
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