Neutrophil Myo5c gene downregulation is associated with postoperative organ dysfunction following pediatric cardiac surgery with cardiopulmonary bypass

Neutrophil Myo5c gene downregulation is associated with postoperative organ dysfunction following pediatric cardiac surgery with cardiopulmonary bypass

IntroductionPediatric cardiac surgery with cardiopulmonary bypass (CPB) carries substantial risks of postoperative organ dysfunction and mortality, making the identification of biomarkers for postoperative organ dysfunction crucial for enhancing patient outcomes. As neutrophils play a major role in...

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Bibliographic Details
Main Authors: Wiriya Maisat, Sumiti Sandhu, Samuel Kim, Hanna Van Pelt, Sek Won Kong, Juan Ibla, Koichi Yuki
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
congenital heart disease
cardiopulmonary bypass
organ injury
myo5c
neutrophil extracellular traps
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1380606/full
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