Assessing the Predictive Power of PIRCHE-II Scores for the Development of De Novo Donor-Specific Antibodies After Simultaneous Pancreas-Kidney Transplantation

Assessing the Predictive Power of PIRCHE-II Scores for the Development of De Novo Donor-Specific Antibodies After Simultaneous Pancreas-Kidney Transplantation

The molecular HLA epitope mismatch is an advanced measure for developing de novo donor-specific antibodies (dnDSA) after kidney transplantation. Its relevance in simultaneous pancreas/kidney transplant recipients (SPKTRs) remains unclear. We investigated dnDSA development in 72 SPKTRs and 383 kidney...

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Bibliographic Details
Main Authors: Francesca Raineri, Lukas Frischknecht, Jakob Nilsson, Fabian Rössler, Claudia Cavelti-Weder, Seraina von Moos, Thomas Schachtner
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Transplant International
Subjects:
simultaneous pancreas and kidney transplant
preformed DSA
de novo DSA
epitope matching
PIRCHE-II score
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13720/full
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