The effects of autologous platelet concentrate on the healing of intra-bony defects: a randomized clinical trial
PurposeThe present study aimed to evaluate the clinical and radiographic effects ofautologous platelet concentrate (APC) on the healing of intra-bony defects filledwith β-tricalcium phosphate (β-TCP) and covered with collagen membranes.Subjects and methodsThis study included 30 defects of 14 systemi...
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Istanbul University
2019-01-01
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| Series: | European Oral Research |
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| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/0330D696BD60465FB1A45486EB0C6BE5 |
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| author | Nitin Kudyar Nitin Dani Shahab Saquib Abullais Nabeeh Alqahtani Aashima Gupta Nilofar Attar |
| author_facet | Nitin Kudyar Nitin Dani Shahab Saquib Abullais Nabeeh Alqahtani Aashima Gupta Nilofar Attar |
| author_sort | Nitin Kudyar |
| collection | DOAJ |
| description | PurposeThe present study aimed to evaluate the clinical and radiographic effects ofautologous platelet concentrate (APC) on the healing of intra-bony defects filledwith β-tricalcium phosphate (β-TCP) and covered with collagen membranes.Subjects and methodsThis study included 30 defects of 14 systemically healthy subjects. All of them had,at least, two deep intra-bony, inter-proximal periodontal defects. Minimum probingpocket depth (PPD) was 6 mm. Clinical and imaging examination was performedboth at baseline and at 3, 6, and 9 months after surgery.ResultsBoth the test and control group revealed a significant reduction in all variableswhen compared with the base line. Mean reduction of the PPD in two groups ateach follow-up time point showed no significant difference. Means of the clinicalattachment gain of the same groups were significantly different (p<0.05). Meangingival recession at 3 month was not significant. However, the means of gingivalrecession coverage of two groups were significantly different at 6 and 9 months(p<0.05 for both).ConclusionSites treated with APC are more likely to demonstrate more clinical attachment gainand recession coverage at the end of 9 month compared to those without APC. |
| format | Article |
| id | doaj-art-96aba007cf474d7284beb32a1b01f7aa |
| institution | DOAJ |
| issn | 2651-2823 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Istanbul University |
| record_format | Article |
| series | European Oral Research |
| spelling | doaj-art-96aba007cf474d7284beb32a1b01f7aa2025-08-20T03:10:57ZengIstanbul UniversityEuropean Oral Research2651-28232019-01-01531384310.26650/eor.20192207101715123456The effects of autologous platelet concentrate on the healing of intra-bony defects: a randomized clinical trialNitin Kudyar0https://orcid.org/0000-0003-4882-6795Nitin Dani1https://orcid.org/0000-0002-4254-6920Shahab Saquib Abullais2https://orcid.org/0000-0002-5223-2167Nabeeh Alqahtani3https://orcid.org/0000-0001-5064-7556Aashima Gupta4https://orcid.org/0000-0002-4367-4844Nilofar Attar5https://orcid.org/0000-0001-6279-3534Himachal Dental College, mandi, IndiaM.G.V Dental College and Hospital, Maharastra, IndiaKing Khalid University, Abha, Saudi-ArabiaKing Khalid University, Abha, Saudi-ArabiaPacific Dental College, Rajasthan, IndiaGovernment Dental College, Mumbai, IndiaPurposeThe present study aimed to evaluate the clinical and radiographic effects ofautologous platelet concentrate (APC) on the healing of intra-bony defects filledwith β-tricalcium phosphate (β-TCP) and covered with collagen membranes.Subjects and methodsThis study included 30 defects of 14 systemically healthy subjects. All of them had,at least, two deep intra-bony, inter-proximal periodontal defects. Minimum probingpocket depth (PPD) was 6 mm. Clinical and imaging examination was performedboth at baseline and at 3, 6, and 9 months after surgery.ResultsBoth the test and control group revealed a significant reduction in all variableswhen compared with the base line. Mean reduction of the PPD in two groups ateach follow-up time point showed no significant difference. Means of the clinicalattachment gain of the same groups were significantly different (p<0.05). Meangingival recession at 3 month was not significant. However, the means of gingivalrecession coverage of two groups were significantly different at 6 and 9 months(p<0.05 for both).ConclusionSites treated with APC are more likely to demonstrate more clinical attachment gainand recession coverage at the end of 9 month compared to those without APC.https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/0330D696BD60465FB1A45486EB0C6BE5intra-bony defectsperiodontal regenerationperiodontitislatelet rich plasmaβ‑tricalcium phosphate |
| spellingShingle | Nitin Kudyar Nitin Dani Shahab Saquib Abullais Nabeeh Alqahtani Aashima Gupta Nilofar Attar The effects of autologous platelet concentrate on the healing of intra-bony defects: a randomized clinical trial European Oral Research intra-bony defects periodontal regeneration periodontitis latelet rich plasma β‑tricalcium phosphate |
| title | The effects of autologous platelet concentrate on the healing of intra-bony defects: a randomized clinical trial |
| title_full | The effects of autologous platelet concentrate on the healing of intra-bony defects: a randomized clinical trial |
| title_fullStr | The effects of autologous platelet concentrate on the healing of intra-bony defects: a randomized clinical trial |
| title_full_unstemmed | The effects of autologous platelet concentrate on the healing of intra-bony defects: a randomized clinical trial |
| title_short | The effects of autologous platelet concentrate on the healing of intra-bony defects: a randomized clinical trial |
| title_sort | effects of autologous platelet concentrate on the healing of intra bony defects a randomized clinical trial |
| topic | intra-bony defects periodontal regeneration periodontitis latelet rich plasma β‑tricalcium phosphate |
| url | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/0330D696BD60465FB1A45486EB0C6BE5 |
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