The effects of autologous platelet concentrate on the healing of intra-bony defects: a randomized clinical trial
PurposeThe present study aimed to evaluate the clinical and radiographic effects ofautologous platelet concentrate (APC) on the healing of intra-bony defects filledwith β-tricalcium phosphate (β-TCP) and covered with collagen membranes.Subjects and methodsThis study included 30 defects of 14 systemi...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Istanbul University
2019-01-01
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| Series: | European Oral Research |
| Subjects: | |
| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/0330D696BD60465FB1A45486EB0C6BE5 |
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| Summary: | PurposeThe present study aimed to evaluate the clinical and radiographic effects ofautologous platelet concentrate (APC) on the healing of intra-bony defects filledwith β-tricalcium phosphate (β-TCP) and covered with collagen membranes.Subjects and methodsThis study included 30 defects of 14 systemically healthy subjects. All of them had,at least, two deep intra-bony, inter-proximal periodontal defects. Minimum probingpocket depth (PPD) was 6 mm. Clinical and imaging examination was performedboth at baseline and at 3, 6, and 9 months after surgery.ResultsBoth the test and control group revealed a significant reduction in all variableswhen compared with the base line. Mean reduction of the PPD in two groups ateach follow-up time point showed no significant difference. Means of the clinicalattachment gain of the same groups were significantly different (p<0.05). Meangingival recession at 3 month was not significant. However, the means of gingivalrecession coverage of two groups were significantly different at 6 and 9 months(p<0.05 for both).ConclusionSites treated with APC are more likely to demonstrate more clinical attachment gainand recession coverage at the end of 9 month compared to those without APC. |
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| ISSN: | 2651-2823 |