Accurate Spatial Heterogeneity Dissection and Gene Regulation Interpretation for Spatial Transcriptomics using Dual Graph Contrastive Learning

Accurate Spatial Heterogeneity Dissection and Gene Regulation Interpretation for Spatial Transcriptomics using Dual Graph Contrastive Learning

Abstract Recent advances in spatial transcriptomics have enabled simultaneous preservation of high‐throughput gene expression profiles and the spatial context, enabling high‐resolution exploration of distinct regional characterization in tissue. To effectively understand the underlying biological me...

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Bibliographic Details
Main Authors:	Zhuohan Yu, Yuning Yang, Xingjian Chen, Ka‐Chun Wong, Zhaolei Zhang, Yuming Zhao, Xiangtao Li
Format:	Article
Language:	English
Published:	Wiley 2025-01-01
Series:	Advanced Science
Subjects:	dual graph contrastive learning gene regulation graph contrastive learning spatial heterogeneity
Online Access:	https://doi.org/10.1002/advs.202410081
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