Vascular leakage during circulatory failure: physiopathology, impact and treatments

Vascular leakage during circulatory failure: physiopathology, impact and treatments

Abstract Vascular leakage has emerged as a major factor during circulatory failure. Triggered by the inflammatory process following the recognition of both pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), it worsens circulatory failure through the hypo...

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Main Authors: Jérémie Joffre, Peter Radermacher, Hatem Kallel, Iris Marangon, Alexandre Rutault, Yaël Levy, Alexandre Gaudet, Benjamine Sarton, Louis Kreitmann, Lucillia Bezu, Meryl Vedrenne, Thomas Maldiney, Youenn Jouan, Sarah Benghanem, Laure Stiel, Stéphane Germain, Nicolas Bréchot, For the ‘commission recherche translationnelle de la société de réanimation de langue française’
Format: Article
Language:English
Published: SpringerOpen 2025-06-01
Series:Annals of Intensive Care
Subjects:
Vascular leakage
Shock
Circulatory failure
Systemic inflammation
Review
Endothelium
Online Access:https://doi.org/10.1186/s13613-025-01474-8
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