Synthesis Methods, Performance Optimization, and Application Progress of Metal–Organic Framework Material MIL-101(Cr)

MIL-101(Cr), a widely studied chromium-based metal–organic framework material consisting of chromium metal ions and terephthalic acid ligands, has attracted much attention due to its ultra-high specific surface area, large pore size, and excellent thermal, chemical, and aqueous stability. The outsta...

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Main Authors: Jiayao Chen, Min Tang, Saiqun Nie, Pengcheng Xiao, Tian Zhao, Yi Chen
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Chemistry
Subjects:
Online Access:https://www.mdpi.com/2624-8549/7/3/78
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author Jiayao Chen
Min Tang
Saiqun Nie
Pengcheng Xiao
Tian Zhao
Yi Chen
author_facet Jiayao Chen
Min Tang
Saiqun Nie
Pengcheng Xiao
Tian Zhao
Yi Chen
author_sort Jiayao Chen
collection DOAJ
description MIL-101(Cr), a widely studied chromium-based metal–organic framework material consisting of chromium metal ions and terephthalic acid ligands, has attracted much attention due to its ultra-high specific surface area, large pore size, and excellent thermal, chemical, and aqueous stability. The outstanding properties and abundant unsaturated Lewis acid sites of this material have shown promising applications in aqueous phase adsorption, gas storage, separation, catalysis, drug delivery, and sensing. In this paper, we systematically review the synthesis technology and performance optimization strategy of MIL-101(Cr), discuss the advantages and limitations of various synthesis methods, such as traditional hydrothermal method, microwave-assisted hydrothermal method, template method, and solvent-thermal method, and summarize and analyze the optimization strategy of MIL-101 from the aspects of physical modification and chemical modification. In addition, this paper summarizes the latest application progress of MIL-101(Cr) in gas adsorption and separation, wastewater purification, pollutant removal, catalysis, and pharmaceutical delivery, and points out the current challenges and future development directions, to provide guidance and inspiration for the industrial application of MIL-101(Cr) and the development of new materials.
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spelling doaj-art-96aa06f28b2c48a5b98b2a5b9db2e1f72025-08-20T02:24:19ZengMDPI AGChemistry2624-85492025-05-01737810.3390/chemistry7030078Synthesis Methods, Performance Optimization, and Application Progress of Metal–Organic Framework Material MIL-101(Cr)Jiayao Chen0Min Tang1Saiqun Nie2Pengcheng Xiao3Tian Zhao4Yi Chen5School of Packaging and Material Engineering, Hunan University of Technology, Zhuzhou 412007, ChinaSchool of Packaging and Material Engineering, Hunan University of Technology, Zhuzhou 412007, ChinaSchool of Packaging and Material Engineering, Hunan University of Technology, Zhuzhou 412007, ChinaSchool of Packaging and Material Engineering, Hunan University of Technology, Zhuzhou 412007, ChinaSchool of Packaging and Material Engineering, Hunan University of Technology, Zhuzhou 412007, ChinaSchool of Packaging and Material Engineering, Hunan University of Technology, Zhuzhou 412007, ChinaMIL-101(Cr), a widely studied chromium-based metal–organic framework material consisting of chromium metal ions and terephthalic acid ligands, has attracted much attention due to its ultra-high specific surface area, large pore size, and excellent thermal, chemical, and aqueous stability. The outstanding properties and abundant unsaturated Lewis acid sites of this material have shown promising applications in aqueous phase adsorption, gas storage, separation, catalysis, drug delivery, and sensing. In this paper, we systematically review the synthesis technology and performance optimization strategy of MIL-101(Cr), discuss the advantages and limitations of various synthesis methods, such as traditional hydrothermal method, microwave-assisted hydrothermal method, template method, and solvent-thermal method, and summarize and analyze the optimization strategy of MIL-101 from the aspects of physical modification and chemical modification. In addition, this paper summarizes the latest application progress of MIL-101(Cr) in gas adsorption and separation, wastewater purification, pollutant removal, catalysis, and pharmaceutical delivery, and points out the current challenges and future development directions, to provide guidance and inspiration for the industrial application of MIL-101(Cr) and the development of new materials.https://www.mdpi.com/2624-8549/7/3/78MIL-101(Cr)synthesis methodsoptimization strategiesapplication advances
spellingShingle Jiayao Chen
Min Tang
Saiqun Nie
Pengcheng Xiao
Tian Zhao
Yi Chen
Synthesis Methods, Performance Optimization, and Application Progress of Metal–Organic Framework Material MIL-101(Cr)
Chemistry
MIL-101(Cr)
synthesis methods
optimization strategies
application advances
title Synthesis Methods, Performance Optimization, and Application Progress of Metal–Organic Framework Material MIL-101(Cr)
title_full Synthesis Methods, Performance Optimization, and Application Progress of Metal–Organic Framework Material MIL-101(Cr)
title_fullStr Synthesis Methods, Performance Optimization, and Application Progress of Metal–Organic Framework Material MIL-101(Cr)
title_full_unstemmed Synthesis Methods, Performance Optimization, and Application Progress of Metal–Organic Framework Material MIL-101(Cr)
title_short Synthesis Methods, Performance Optimization, and Application Progress of Metal–Organic Framework Material MIL-101(Cr)
title_sort synthesis methods performance optimization and application progress of metal organic framework material mil 101 cr
topic MIL-101(Cr)
synthesis methods
optimization strategies
application advances
url https://www.mdpi.com/2624-8549/7/3/78
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AT pengchengxiao synthesismethodsperformanceoptimizationandapplicationprogressofmetalorganicframeworkmaterialmil101cr
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