The environmental risk factors associated with fetal macrosomia: An umbrella review
The present umbrella review evaluated the environmental risk factors prior to conception associated with fetal macrosomia based on meta-analyses and systematic reviews. We systematically searched international databases, including PubMed, Scopus, and Web of Science, until April 2023 by using some re...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-05-01
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| Series: | Pediatrics and Neonatology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S187595722300222X |
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| author | Ensiyeh Jenabi Amir Mohammad Salehi Sajjad Farashi Zohreh Salimi |
| author_facet | Ensiyeh Jenabi Amir Mohammad Salehi Sajjad Farashi Zohreh Salimi |
| author_sort | Ensiyeh Jenabi |
| collection | DOAJ |
| description | The present umbrella review evaluated the environmental risk factors prior to conception associated with fetal macrosomia based on meta-analyses and systematic reviews. We systematically searched international databases, including PubMed, Scopus, and Web of Science, until April 2023 by using some relevant keywords. The quality of the included studies was assessed using the AMSTAR 2checklist. The risk factor of advanced maternal age 35–39 years compared with <30 years (OR 1·42, 95 % CI: 1·25, 1·60), prepregnancy obesity (OR 1.93, 95 % CI: 1.65, 2.27) and excessive weight gain before and during pregnancy (OR 2.35, 95 % CI: 1.95, 2.85) were graded as suggestive evidence (class III). Two risk factors of advanced maternal age >40 years compared with <30 years (OR 1.40, 95 % CI: 1.02, 1.78) and gestational diabetes mellitus (GDM) without insulin use (OR 1.70, 95 % CI: 1.23, 2.36) were graded as risk factors with weak evidence (class IV). Advanced maternal age, prepregnancy obesity, excessive weight gain before and during pregnancy, and GDM without insulin use were environmental risk factors for macrosomia. |
| format | Article |
| id | doaj-art-96a810d424a04fe4a42221894e8fccd1 |
| institution | DOAJ |
| issn | 1875-9572 |
| language | English |
| publishDate | 2024-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj-art-96a810d424a04fe4a42221894e8fccd12025-08-20T03:19:53ZengElsevierPediatrics and Neonatology1875-95722024-05-0165321722110.1016/j.pedneo.2023.09.007The environmental risk factors associated with fetal macrosomia: An umbrella reviewEnsiyeh Jenabi0Amir Mohammad Salehi1Sajjad Farashi2Zohreh Salimi3Mother and Child Care Research Center, Hamadan University of Medical Sciences, Hamadan, IranStudent Research Committee, Hamadan University of Medical Sciences School of Medicine, Hamadan, Iran; Corresponding author. Hamadan University of Medical Sciences School of medicine, Hamadan, 6517838736, Iran.Autism Spectrum Disorder Research Center, Hamadan University of Medical Sciences, Hamadan, IranAutism Spectrum Disorder Research Center, Hamadan University of Medical Sciences, Hamadan, IranThe present umbrella review evaluated the environmental risk factors prior to conception associated with fetal macrosomia based on meta-analyses and systematic reviews. We systematically searched international databases, including PubMed, Scopus, and Web of Science, until April 2023 by using some relevant keywords. The quality of the included studies was assessed using the AMSTAR 2checklist. The risk factor of advanced maternal age 35–39 years compared with <30 years (OR 1·42, 95 % CI: 1·25, 1·60), prepregnancy obesity (OR 1.93, 95 % CI: 1.65, 2.27) and excessive weight gain before and during pregnancy (OR 2.35, 95 % CI: 1.95, 2.85) were graded as suggestive evidence (class III). Two risk factors of advanced maternal age >40 years compared with <30 years (OR 1.40, 95 % CI: 1.02, 1.78) and gestational diabetes mellitus (GDM) without insulin use (OR 1.70, 95 % CI: 1.23, 2.36) were graded as risk factors with weak evidence (class IV). Advanced maternal age, prepregnancy obesity, excessive weight gain before and during pregnancy, and GDM without insulin use were environmental risk factors for macrosomia.http://www.sciencedirect.com/science/article/pii/S187595722300222XMacrosomiaMeta-analysisRisk factorsUmbrella study |
| spellingShingle | Ensiyeh Jenabi Amir Mohammad Salehi Sajjad Farashi Zohreh Salimi The environmental risk factors associated with fetal macrosomia: An umbrella review Pediatrics and Neonatology Macrosomia Meta-analysis Risk factors Umbrella study |
| title | The environmental risk factors associated with fetal macrosomia: An umbrella review |
| title_full | The environmental risk factors associated with fetal macrosomia: An umbrella review |
| title_fullStr | The environmental risk factors associated with fetal macrosomia: An umbrella review |
| title_full_unstemmed | The environmental risk factors associated with fetal macrosomia: An umbrella review |
| title_short | The environmental risk factors associated with fetal macrosomia: An umbrella review |
| title_sort | environmental risk factors associated with fetal macrosomia an umbrella review |
| topic | Macrosomia Meta-analysis Risk factors Umbrella study |
| url | http://www.sciencedirect.com/science/article/pii/S187595722300222X |
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