Orbital Swelling and Ptosis as an Initial Presentation of Childhood Acute Lymphoblastic Leukaemia: A Case Report and Review of the Literature

We are reporting the case of a 3-year-old-girl who initially presented with unilateral eyelid swelling and ptosis. A diagnosis of acute lymphoblastic leukaemia (ALL) was eventually made based on an orbital incisional biopsy and a bone marrow examination. Historically, orbital involvement had been li...

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Main Authors: Ahmed Alsalem, Bayan Almasoudi, Ghaida Alzahrani, Lama Sindi, Joud Alwan
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2021/5587767
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author Ahmed Alsalem
Bayan Almasoudi
Ghaida Alzahrani
Lama Sindi
Joud Alwan
author_facet Ahmed Alsalem
Bayan Almasoudi
Ghaida Alzahrani
Lama Sindi
Joud Alwan
author_sort Ahmed Alsalem
collection DOAJ
description We are reporting the case of a 3-year-old-girl who initially presented with unilateral eyelid swelling and ptosis. A diagnosis of acute lymphoblastic leukaemia (ALL) was eventually made based on an orbital incisional biopsy and a bone marrow examination. Historically, orbital involvement had been linked to myeloid leukaemia; however, in lymphoid leukaemia, they are increasingly being implicated and had been reported as the sole presentation of the disease. These findings stress the importance of conducting ophthalmologic assessments in cases diagnosed with ALL in order to prevent delays in proper assessment and treatment. Management options in orbital disease are fortunately not significantly different than well-established treatment protocols.
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institution Kabale University
issn 2090-6803
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language English
publishDate 2021-01-01
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series Case Reports in Pediatrics
spelling doaj-art-96a2dc3e8d734aba8207230b7195d3982025-08-20T03:37:30ZengWileyCase Reports in Pediatrics2090-68032090-68112021-01-01202110.1155/2021/55877675587767Orbital Swelling and Ptosis as an Initial Presentation of Childhood Acute Lymphoblastic Leukaemia: A Case Report and Review of the LiteratureAhmed Alsalem0Bayan Almasoudi1Ghaida Alzahrani2Lama Sindi3Joud Alwan4Department of Ophthalmology, Prince Sultan Military Medical City, Riyadh, Saudi ArabiaDepartment of Ophthalmology, Prince Sultan Military Medical City, Riyadh, Saudi ArabiaCollege of Medicine, Umm Al-Qura University, Makkah, Saudi ArabiaCollege of Medicine, Umm Al-Qura University, Makkah, Saudi ArabiaCollege of Medicine, Umm Al-Qura University, Makkah, Saudi ArabiaWe are reporting the case of a 3-year-old-girl who initially presented with unilateral eyelid swelling and ptosis. A diagnosis of acute lymphoblastic leukaemia (ALL) was eventually made based on an orbital incisional biopsy and a bone marrow examination. Historically, orbital involvement had been linked to myeloid leukaemia; however, in lymphoid leukaemia, they are increasingly being implicated and had been reported as the sole presentation of the disease. These findings stress the importance of conducting ophthalmologic assessments in cases diagnosed with ALL in order to prevent delays in proper assessment and treatment. Management options in orbital disease are fortunately not significantly different than well-established treatment protocols.http://dx.doi.org/10.1155/2021/5587767
spellingShingle Ahmed Alsalem
Bayan Almasoudi
Ghaida Alzahrani
Lama Sindi
Joud Alwan
Orbital Swelling and Ptosis as an Initial Presentation of Childhood Acute Lymphoblastic Leukaemia: A Case Report and Review of the Literature
Case Reports in Pediatrics
title Orbital Swelling and Ptosis as an Initial Presentation of Childhood Acute Lymphoblastic Leukaemia: A Case Report and Review of the Literature
title_full Orbital Swelling and Ptosis as an Initial Presentation of Childhood Acute Lymphoblastic Leukaemia: A Case Report and Review of the Literature
title_fullStr Orbital Swelling and Ptosis as an Initial Presentation of Childhood Acute Lymphoblastic Leukaemia: A Case Report and Review of the Literature
title_full_unstemmed Orbital Swelling and Ptosis as an Initial Presentation of Childhood Acute Lymphoblastic Leukaemia: A Case Report and Review of the Literature
title_short Orbital Swelling and Ptosis as an Initial Presentation of Childhood Acute Lymphoblastic Leukaemia: A Case Report and Review of the Literature
title_sort orbital swelling and ptosis as an initial presentation of childhood acute lymphoblastic leukaemia a case report and review of the literature
url http://dx.doi.org/10.1155/2021/5587767
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