Facilitators and barriers to maternal immunization and strategies to improve uptake in low-income and lower-middle income countries: A systematic review

Maternal immunization (MI) is an emerging strategy to combat infant mortality in low-income (LIC) and lower-middle income countries (LMIC). We conducted a systematic review to identify the facilitators and barriers to MI and strategies that improve uptake in LICs and LMICs. We searched PubMed, Cochr...

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Main Authors: Tila Khan, Simran Malik, Liya Rafeekh, Sayantan Halder, Sapna Desai, Sangeeta Das Bhattacharya
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Human Vaccines & Immunotherapeutics
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Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2024.2411823
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author Tila Khan
Simran Malik
Liya Rafeekh
Sayantan Halder
Sapna Desai
Sangeeta Das Bhattacharya
author_facet Tila Khan
Simran Malik
Liya Rafeekh
Sayantan Halder
Sapna Desai
Sangeeta Das Bhattacharya
author_sort Tila Khan
collection DOAJ
description Maternal immunization (MI) is an emerging strategy to combat infant mortality in low-income (LIC) and lower-middle income countries (LMIC). We conducted a systematic review to identify the facilitators and barriers to MI and strategies that improve uptake in LICs and LMICs. We searched PubMed, Cochrane Library, and Scopus for quantitative, qualitative, and mixed-methods studies published in English from January 1, 2011, to October 31, 2021, from all LICs and LMICs. Data was appraised using the Mixed Methods Appraisal Tool. 55 studies were included. The major barriers were low knowledge and concern of vaccine safety among pregnant women and healthcare providers (HCP). HCP’s recommendation, maternal knowledge, vaccine confidence and ≥4 antenatal care (ANC) visits facilitated uptake. The key strategies encompassed health financing, reminders, intersectoral coordination, integration, community engagement, capacity building, and education. Community-based delivery models were effective. Tailored programs are needed to improve ANC access, and educate pregnant women and HCPs.
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publishDate 2024-12-01
publisher Taylor & Francis Group
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series Human Vaccines & Immunotherapeutics
spelling doaj-art-96a295ccf8ce49fba57df522f416407a2025-08-20T03:12:43ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2024-12-0120110.1080/21645515.2024.2411823Facilitators and barriers to maternal immunization and strategies to improve uptake in low-income and lower-middle income countries: A systematic reviewTila Khan0Simran Malik1Liya Rafeekh2Sayantan Halder3Sapna Desai4Sangeeta Das Bhattacharya5School of Medical Science & Technology, Indian Institute of Technology, Kharagpur, IndiaSchool of Medical Science & Technology, Indian Institute of Technology, Kharagpur, IndiaSchool of Medical Science & Technology, Indian Institute of Technology, Kharagpur, IndiaSchool of Medical Science & Technology, Indian Institute of Technology, Kharagpur, IndiaPopulation Council Institute, New Delhi, IndiaSchool of Medical Science & Technology, Indian Institute of Technology, Kharagpur, IndiaMaternal immunization (MI) is an emerging strategy to combat infant mortality in low-income (LIC) and lower-middle income countries (LMIC). We conducted a systematic review to identify the facilitators and barriers to MI and strategies that improve uptake in LICs and LMICs. We searched PubMed, Cochrane Library, and Scopus for quantitative, qualitative, and mixed-methods studies published in English from January 1, 2011, to October 31, 2021, from all LICs and LMICs. Data was appraised using the Mixed Methods Appraisal Tool. 55 studies were included. The major barriers were low knowledge and concern of vaccine safety among pregnant women and healthcare providers (HCP). HCP’s recommendation, maternal knowledge, vaccine confidence and ≥4 antenatal care (ANC) visits facilitated uptake. The key strategies encompassed health financing, reminders, intersectoral coordination, integration, community engagement, capacity building, and education. Community-based delivery models were effective. Tailored programs are needed to improve ANC access, and educate pregnant women and HCPs.https://www.tandfonline.com/doi/10.1080/21645515.2024.2411823BarrierfacilitatorLICLMICpregnancystrategies
spellingShingle Tila Khan
Simran Malik
Liya Rafeekh
Sayantan Halder
Sapna Desai
Sangeeta Das Bhattacharya
Facilitators and barriers to maternal immunization and strategies to improve uptake in low-income and lower-middle income countries: A systematic review
Human Vaccines & Immunotherapeutics
Barrier
facilitator
LIC
LMIC
pregnancy
strategies
title Facilitators and barriers to maternal immunization and strategies to improve uptake in low-income and lower-middle income countries: A systematic review
title_full Facilitators and barriers to maternal immunization and strategies to improve uptake in low-income and lower-middle income countries: A systematic review
title_fullStr Facilitators and barriers to maternal immunization and strategies to improve uptake in low-income and lower-middle income countries: A systematic review
title_full_unstemmed Facilitators and barriers to maternal immunization and strategies to improve uptake in low-income and lower-middle income countries: A systematic review
title_short Facilitators and barriers to maternal immunization and strategies to improve uptake in low-income and lower-middle income countries: A systematic review
title_sort facilitators and barriers to maternal immunization and strategies to improve uptake in low income and lower middle income countries a systematic review
topic Barrier
facilitator
LIC
LMIC
pregnancy
strategies
url https://www.tandfonline.com/doi/10.1080/21645515.2024.2411823
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