Unexpected hope for a multiple myeloma patient

Multiple myeloma (MM) is a plasma cell neoplasm, characterized by periods of remission and relapses. The emergence of novel therapies, with multiple mechanisms of action and fewer adverse reactions, brings more and better options and also a higher survival rate. However, MM is still an incurable dis...

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Main Authors: Minodora Cezarina Onisâi, Iuliana Iordan, Mihaela Gaman, Horia Bumbea, Ana-Maria Vlădăreanu
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Journal of Mind and Medical Sciences
Subjects:
Online Access:https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1255&context=jmms
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author Minodora Cezarina Onisâi
Iuliana Iordan
Mihaela Gaman
Horia Bumbea
Ana-Maria Vlădăreanu
author_facet Minodora Cezarina Onisâi
Iuliana Iordan
Mihaela Gaman
Horia Bumbea
Ana-Maria Vlădăreanu
author_sort Minodora Cezarina Onisâi
collection DOAJ
description Multiple myeloma (MM) is a plasma cell neoplasm, characterized by periods of remission and relapses. The emergence of novel therapies, with multiple mechanisms of action and fewer adverse reactions, brings more and better options and also a higher survival rate. However, MM is still an incurable disease, and patients eventually become refractory to an extensive range of therapies. We present the case of a patient diagnosed with MM standard risk, who was at first refractory to multiple treatment regimens, and then had an unexpected and stable complete response to a newer drug of the same class.
format Article
id doaj-art-9696df851f4f41d8a6d033583fc52967
institution DOAJ
issn 2392-7674
2392-7674
language English
publishDate 2020-10-01
publisher MDPI AG
record_format Article
series Journal of Mind and Medical Sciences
spelling doaj-art-9696df851f4f41d8a6d033583fc529672025-08-20T03:09:55ZengMDPI AGJournal of Mind and Medical Sciences2392-76742392-76742020-10-017225726010.22543/7674.72.P257260Unexpected hope for a multiple myeloma patientMinodora Cezarina Onisâi0Iuliana Iordan1Mihaela Gaman2Horia Bumbea3Ana-Maria Vlădăreanu4CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, BUCHAREST, ROMANIACAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, BUCHAREST, ROMANIACAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, BUCHAREST, ROMANIACAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, BUCHAREST, ROMANIACAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, BUCHAREST, ROMANIAMultiple myeloma (MM) is a plasma cell neoplasm, characterized by periods of remission and relapses. The emergence of novel therapies, with multiple mechanisms of action and fewer adverse reactions, brings more and better options and also a higher survival rate. However, MM is still an incurable disease, and patients eventually become refractory to an extensive range of therapies. We present the case of a patient diagnosed with MM standard risk, who was at first refractory to multiple treatment regimens, and then had an unexpected and stable complete response to a newer drug of the same class.https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1255&context=jmmsmultiple myelomarefractoryproteasome inhibitors
spellingShingle Minodora Cezarina Onisâi
Iuliana Iordan
Mihaela Gaman
Horia Bumbea
Ana-Maria Vlădăreanu
Unexpected hope for a multiple myeloma patient
Journal of Mind and Medical Sciences
multiple myeloma
refractory
proteasome inhibitors
title Unexpected hope for a multiple myeloma patient
title_full Unexpected hope for a multiple myeloma patient
title_fullStr Unexpected hope for a multiple myeloma patient
title_full_unstemmed Unexpected hope for a multiple myeloma patient
title_short Unexpected hope for a multiple myeloma patient
title_sort unexpected hope for a multiple myeloma patient
topic multiple myeloma
refractory
proteasome inhibitors
url https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1255&context=jmms
work_keys_str_mv AT minodoracezarinaonisai unexpectedhopeforamultiplemyelomapatient
AT iulianaiordan unexpectedhopeforamultiplemyelomapatient
AT mihaelagaman unexpectedhopeforamultiplemyelomapatient
AT horiabumbea unexpectedhopeforamultiplemyelomapatient
AT anamariavladareanu unexpectedhopeforamultiplemyelomapatient