Transfer learning for accurate brain tumor classification in MRI: a step forward in medical diagnostics

Abstract Brain tumor classification is critical for therapeutic applications that benefit from computer-aided diagnostics. Misdiagnosing a brain tumor can significantly reduce a patient's chances of survival, as it may lead to ineffective treatments. This study proposes a novel approach for cla...

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Main Authors: Muhammad Adnan Khan, Muhammad Zahid Hussain, Shahid Mehmood, Muhammad Farhan Khan, Munir Ahmad, Tehseen Mazhar, Tariq Shahzad, Mamoon M. Saeed
Format: Article
Language:English
Published: Springer 2025-06-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-025-02671-4
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author Muhammad Adnan Khan
Muhammad Zahid Hussain
Shahid Mehmood
Muhammad Farhan Khan
Munir Ahmad
Tehseen Mazhar
Tariq Shahzad
Mamoon M. Saeed
author_facet Muhammad Adnan Khan
Muhammad Zahid Hussain
Shahid Mehmood
Muhammad Farhan Khan
Munir Ahmad
Tehseen Mazhar
Tariq Shahzad
Mamoon M. Saeed
author_sort Muhammad Adnan Khan
collection DOAJ
description Abstract Brain tumor classification is critical for therapeutic applications that benefit from computer-aided diagnostics. Misdiagnosing a brain tumor can significantly reduce a patient's chances of survival, as it may lead to ineffective treatments. This study proposes a novel approach for classifying brain tumors in MRI images using Transfer Learning (TL) with state-of-the-art deep learning models: AlexNet, MobileNetV2, and GoogleNet. Unlike previous studies that often focus on a single model, our work comprehensively compares these architectures, fine-tuned specifically for brain tumor classification. We utilize a publicly available dataset of 4,517 MRI scans, consisting of three prevalent types of brain tumors—glioma (1,129 images), meningioma (1,134 images), and pituitary tumors (1,138 images)—as well as 1,116 images of normal brains (no tumor). Our approach addresses key research gaps, including class imbalance, through data augmentation and model efficiency, leveraging lightweight architectures like MobileNetV2. The GoogleNet model achieves the highest classification accuracy of 99.2%, outperforming previous studies using the same dataset. This demonstrates the potential of our approach to assist physicians in making rapid and precise decisions, thereby improving patient outcomes. The results highlight the effectiveness of TL in medical diagnostics and its potential for real-world clinical deployment. This study advances the field of brain tumor classification and provides a robust framework for future research in medical image analysis.
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spelling doaj-art-9690a6287c9e499e99201255f69c6d912025-08-20T02:06:36ZengSpringerDiscover Oncology2730-60112025-06-0116111610.1007/s12672-025-02671-4Transfer learning for accurate brain tumor classification in MRI: a step forward in medical diagnosticsMuhammad Adnan Khan0Muhammad Zahid Hussain1Shahid Mehmood2Muhammad Farhan Khan3Munir Ahmad4Tehseen Mazhar5Tariq Shahzad6Mamoon M. Saeed7Department of Software, Faculty of Artificial Intelligence and Software, Gachon UniversityFaculty of Information Technology and Computer Science, University of Central PunjabDepartment of Computer Science, Bahria University, Lahore CampusDepartment of Forensic Sciences, University of Health SciencesUniversity College, Korea UniversitySchool of Computer Science, National College of Business Administration and EconomicsDepartment of Computer Engineering, COMSATS University Islamabad, Sahiwal CampusDepartment of Communications and Electronics Engineering, Faculty of Engineering, University of Modern Sciences (UMS)Abstract Brain tumor classification is critical for therapeutic applications that benefit from computer-aided diagnostics. Misdiagnosing a brain tumor can significantly reduce a patient's chances of survival, as it may lead to ineffective treatments. This study proposes a novel approach for classifying brain tumors in MRI images using Transfer Learning (TL) with state-of-the-art deep learning models: AlexNet, MobileNetV2, and GoogleNet. Unlike previous studies that often focus on a single model, our work comprehensively compares these architectures, fine-tuned specifically for brain tumor classification. We utilize a publicly available dataset of 4,517 MRI scans, consisting of three prevalent types of brain tumors—glioma (1,129 images), meningioma (1,134 images), and pituitary tumors (1,138 images)—as well as 1,116 images of normal brains (no tumor). Our approach addresses key research gaps, including class imbalance, through data augmentation and model efficiency, leveraging lightweight architectures like MobileNetV2. The GoogleNet model achieves the highest classification accuracy of 99.2%, outperforming previous studies using the same dataset. This demonstrates the potential of our approach to assist physicians in making rapid and precise decisions, thereby improving patient outcomes. The results highlight the effectiveness of TL in medical diagnostics and its potential for real-world clinical deployment. This study advances the field of brain tumor classification and provides a robust framework for future research in medical image analysis.https://doi.org/10.1007/s12672-025-02671-4AlexNetBrain tumor classificationGoogleNetMobileNetv2Transfer learningDeep learning
spellingShingle Muhammad Adnan Khan
Muhammad Zahid Hussain
Shahid Mehmood
Muhammad Farhan Khan
Munir Ahmad
Tehseen Mazhar
Tariq Shahzad
Mamoon M. Saeed
Transfer learning for accurate brain tumor classification in MRI: a step forward in medical diagnostics
Discover Oncology
AlexNet
Brain tumor classification
GoogleNet
MobileNetv2
Transfer learning
Deep learning
title Transfer learning for accurate brain tumor classification in MRI: a step forward in medical diagnostics
title_full Transfer learning for accurate brain tumor classification in MRI: a step forward in medical diagnostics
title_fullStr Transfer learning for accurate brain tumor classification in MRI: a step forward in medical diagnostics
title_full_unstemmed Transfer learning for accurate brain tumor classification in MRI: a step forward in medical diagnostics
title_short Transfer learning for accurate brain tumor classification in MRI: a step forward in medical diagnostics
title_sort transfer learning for accurate brain tumor classification in mri a step forward in medical diagnostics
topic AlexNet
Brain tumor classification
GoogleNet
MobileNetv2
Transfer learning
Deep learning
url https://doi.org/10.1007/s12672-025-02671-4
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