Gestational diabetes induces autistic-like behaviors in offspring by disrupting the GABAergic system

Gestational diabetes induces autistic-like behaviors in offspring by disrupting the GABAergic system

BackgroundIncreasing evidence have shown that gestational diabetes mellitus (GDM) is associated with the risk of autism in offspring. However, the underlying mechanisms have not yet been fully elucidated.MethodsA mouse model of gestational diabetes mellitus (GDM) was established to investigate its i...

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Main Authors: Xuan-Qi Liu, Tian-li Huang, Shu-Yu Zhang, Yu-Tong Huang, Jia-Ying Mo, Yi-Shang Yan, Yi-Ning Cao, Yue-Ran Cai, Jian-Zhong Sheng, Hong Zhu, He Feng Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Neuroscience
Subjects:
gestational diabetes (GDM)
autism
neurodevelopment
GABA
behavior
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2025.1538115/full
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