Early life origins of all-cause and cause-specific disability pension: findings from the Helsinki Birth Cohort Study.
<h4>Background</h4>There is some evidence linking sub-optimal prenatal development to an increased risk of disability pension (DP). Our aim was to investigate whether body size at birth was associated with transitioning into all-cause and cause-specific DP during the adult work career.&l...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0122134 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850125367335976960 |
|---|---|
| author | Mikaela B von Bondorff Timo Törmäkangas Minna Salonen Monika E von Bonsdorff Clive Osmond Eero Kajantie Johan G Eriksson |
| author_facet | Mikaela B von Bondorff Timo Törmäkangas Minna Salonen Monika E von Bonsdorff Clive Osmond Eero Kajantie Johan G Eriksson |
| author_sort | Mikaela B von Bondorff |
| collection | DOAJ |
| description | <h4>Background</h4>There is some evidence linking sub-optimal prenatal development to an increased risk of disability pension (DP). Our aim was to investigate whether body size at birth was associated with transitioning into all-cause and cause-specific DP during the adult work career.<h4>Methods</h4>10 682 people born in 1934-44 belonging to the Helsinki Birth Cohort Study had data on birth weight extracted from birth records, and on time, type and reason of retirement between 1971 and 2011 extracted from the Finnish Centre for Pensions.<h4>Results</h4>Altogether 21.3% transitioned into DP during the 40-year follow-up, mainly due to mental disorders, musculoskeletal disorders and cardiovascular disease. Average age of transitioning into DP was 51.3 (SD 8.4) for men and 52.2 (SD 7.6) for women. Cohort members who did not transition into DP retired 10 years later on average. Among men, higher birth weight was associated with a lower hazard of transitioning into DP, adjusted hazard ratio (HR) being 0.94 (95% confidence interval [CI] 0.88-0.99 for 1 SD increase in birth weight). For DP due to mental disorders the adjusted HR was 0.90, 95% CI 0.81, 0.99. A similar but non-significant trend was found for DP due to cardiovascular disease. Among women there were no associations between body size at birth and all-cause DP (p for interaction gender*birth weight on DP p = 0.007).<h4>Conclusions</h4>Among men disability pension, particularly due to mental disorders, may have its origins in prenatal development. Given that those who retire due to mental health problems are relatively young, the loss to the workforce is substantial. |
| format | Article |
| id | doaj-art-96879b79b3c848df9243bd6d39b786d7 |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-96879b79b3c848df9243bd6d39b786d72025-08-20T02:34:07ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01104e012213410.1371/journal.pone.0122134Early life origins of all-cause and cause-specific disability pension: findings from the Helsinki Birth Cohort Study.Mikaela B von BondorffTimo TörmäkangasMinna SalonenMonika E von BonsdorffClive OsmondEero KajantieJohan G Eriksson<h4>Background</h4>There is some evidence linking sub-optimal prenatal development to an increased risk of disability pension (DP). Our aim was to investigate whether body size at birth was associated with transitioning into all-cause and cause-specific DP during the adult work career.<h4>Methods</h4>10 682 people born in 1934-44 belonging to the Helsinki Birth Cohort Study had data on birth weight extracted from birth records, and on time, type and reason of retirement between 1971 and 2011 extracted from the Finnish Centre for Pensions.<h4>Results</h4>Altogether 21.3% transitioned into DP during the 40-year follow-up, mainly due to mental disorders, musculoskeletal disorders and cardiovascular disease. Average age of transitioning into DP was 51.3 (SD 8.4) for men and 52.2 (SD 7.6) for women. Cohort members who did not transition into DP retired 10 years later on average. Among men, higher birth weight was associated with a lower hazard of transitioning into DP, adjusted hazard ratio (HR) being 0.94 (95% confidence interval [CI] 0.88-0.99 for 1 SD increase in birth weight). For DP due to mental disorders the adjusted HR was 0.90, 95% CI 0.81, 0.99. A similar but non-significant trend was found for DP due to cardiovascular disease. Among women there were no associations between body size at birth and all-cause DP (p for interaction gender*birth weight on DP p = 0.007).<h4>Conclusions</h4>Among men disability pension, particularly due to mental disorders, may have its origins in prenatal development. Given that those who retire due to mental health problems are relatively young, the loss to the workforce is substantial.https://doi.org/10.1371/journal.pone.0122134 |
| spellingShingle | Mikaela B von Bondorff Timo Törmäkangas Minna Salonen Monika E von Bonsdorff Clive Osmond Eero Kajantie Johan G Eriksson Early life origins of all-cause and cause-specific disability pension: findings from the Helsinki Birth Cohort Study. PLoS ONE |
| title | Early life origins of all-cause and cause-specific disability pension: findings from the Helsinki Birth Cohort Study. |
| title_full | Early life origins of all-cause and cause-specific disability pension: findings from the Helsinki Birth Cohort Study. |
| title_fullStr | Early life origins of all-cause and cause-specific disability pension: findings from the Helsinki Birth Cohort Study. |
| title_full_unstemmed | Early life origins of all-cause and cause-specific disability pension: findings from the Helsinki Birth Cohort Study. |
| title_short | Early life origins of all-cause and cause-specific disability pension: findings from the Helsinki Birth Cohort Study. |
| title_sort | early life origins of all cause and cause specific disability pension findings from the helsinki birth cohort study |
| url | https://doi.org/10.1371/journal.pone.0122134 |
| work_keys_str_mv | AT mikaelabvonbondorff earlylifeoriginsofallcauseandcausespecificdisabilitypensionfindingsfromthehelsinkibirthcohortstudy AT timotormakangas earlylifeoriginsofallcauseandcausespecificdisabilitypensionfindingsfromthehelsinkibirthcohortstudy AT minnasalonen earlylifeoriginsofallcauseandcausespecificdisabilitypensionfindingsfromthehelsinkibirthcohortstudy AT monikaevonbonsdorff earlylifeoriginsofallcauseandcausespecificdisabilitypensionfindingsfromthehelsinkibirthcohortstudy AT cliveosmond earlylifeoriginsofallcauseandcausespecificdisabilitypensionfindingsfromthehelsinkibirthcohortstudy AT eerokajantie earlylifeoriginsofallcauseandcausespecificdisabilitypensionfindingsfromthehelsinkibirthcohortstudy AT johangeriksson earlylifeoriginsofallcauseandcausespecificdisabilitypensionfindingsfromthehelsinkibirthcohortstudy |